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Safety Information

ABN442

Sigma-Aldrich

Anti-FGF-20 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Fibroblast growth factor 20, FGF-20

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

species reactivity (predicted by homology)

guinea pig (based on 100% sequence homology), ferret (based on 100% sequence homology), mouse (based on 100% sequence homology), rat (based on 100% sequence homology)

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... FGF20(26281)

General description

FGF-20 is a recent but important neurotrophic factor that regulates multiple central nervous system developmental systems and cell functions. It is a secreted protein expressed most highly in the cerebellum but also found in other regions. FGF-20 is a pro-survival factor on neurons and specifically has been shown to protect dopaminergic neurons against a range of toxic insults in vitro, through activation of fibroblast growth factor receptor 1 (FGFR1). FGF-20 treatments also appear to protect neurons in various disease models so it is being studied as a possible therapy.

Immunogen

KLH-conjugated linear peptide corresponding to human FGF-20 near theC-terminal.

Application

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected FGF-20 in human cerebral cortex, human cerebellum, and human thalamus tissue.
This Anti-FGF-20 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of FGF-20.

Quality

Evaluated by Western Blotting in transfected HEK293 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected FGF-20 in 10 µg of transfected HEK293 cell lysate.

Target description

~30 kDa observed. Uncharacterized band(s) may appear in some lysates.

Other Notes

Concentration: Please refer to lot specific datasheet.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

ABN442:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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