ABC427

Anti-ANT2 Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): ADP/ATP translocase 2, ADP,ATP carrier protein 2, ADP,ATP carrier protein, fibroblast isoform, Adenine nucleotide translocator 2, ANT 2, Solute carrier family 25 member 5, ADP/ATP translocase 2, N-terminally processed
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human
• species reactivity (predicted by homology): avian (based on 100% sequence homology), fish (based on 100% sequence homology), nonhuman primates (based on 100% sequence homology), chicken (based on 100% sequence homology), rat (based on 100% sequence homology)
• technique(s): immunocytochemistry: suitable; western blot: suitable
• NCBI accession no.: NP_001143
• UniProt accession no.: P05141
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... SLC25A5(292)

Description

General description

ANT2, also known as ADP/ATP translocase 2, ADP, ATP carrier protein 2, ADP, ATP carrier protein, fibroblast isoform, Adenine nucleotide translocator 2, ANT 2, Solute carrier family 25 member 5, and encoded by the gene symbol SLC25A5/ ANT2 is a member of the mitochondrial carrier (TC 2.A.29) family. ANT2 has been implied to catalyze the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex, ANT2 may play a role in chromosome segregation. ANT2 is a homodimer and a component of the MMXD complex, which includes CIAO1, ERCC2, FAM96B, MMS19 and SLC25A5. Recent studies have indicated that ANT2 interacts with HIV-1 Vpr. ANT2 is a multi-pass membrane protein and is located in the mitochondrion inner membrane.

Immunogen

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human ANT2.

Application

Anti-ANT2 is an antibody against ANT2 for use in WB, ICC.

Immunocytochemistry Analysis: A 1:1,000 dilution from a representative lot detected ANT2 in SK-BR3 cells.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Quality

Evaluated by Western Blotting in SK-BR3 cell lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected ANT2 in 10 µg of SK-BR3 cell lysate.

Target description

~30 kDa observed

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Other Notes

Concentration: Please refer to lot specific datasheet.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable