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AB9904

Sigma-Aldrich

Anti-QKI-5 Antibody

serum, Chemicon®

Synonym(s):

Quaking Protein

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, human, rat

manufacturer/tradename

Chemicon®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

NCBI accession no.

NM_006775.1
NM_206853.1
NM_206854.1
NM_206855.1

UniProt accession no.

Q96PU8

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... QKI(9444)

General description

QKI is an RNA-binding protein that plays a central role in myelinization. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. It is regulated by alternative splicing.

Specificity

QKI-5 (Quaking Protein). The antibody recognizes the ~40 kDa protein.

Immunogen

Synthetic peptide from mouse QKI-5.

Application

Detect QKI-5 using this Anti-QKI-5 Antibody validated for use in IP & WB.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience

RNA Binding Protein (RBP)

Target description

~40 kDa

Physical form

Liquid.
Serum

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

Analysis Note

Control
Positive Control: Glial cells, astrocytes and oligodendrocytes.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

AB9904:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fang Wang et al.
Cell research, 27(3), 416-439 (2017-03-01)
MicroRNA (miRNA) biogenesis is finely controlled by complex layers of post-transcriptional regulators, including RNA-binding proteins (RBPs). Here, we show that an RBP, QKI5, activates the processing of primary miR-124-1 (pri-124-1) during erythropoiesis. QKI5 recognizes a distal QKI response element and
Xingyu Yang et al.
Journal of cellular and molecular medicine, 25(12), 5655-5670 (2021-05-05)
Preeclampsia (PE) is characterized by placental ischemia and hypoxia, resulting in abnormal casting of the uterine spiral artery, which is mainly caused by insufficient trophoblastic cell infiltration. A reduction in levels of growth factor-based signalling via Neuropilin-1 (NRP1) has been
Benjamin Rauwel et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 35(4), 753-765 (2019-12-14)
Increased osteoclastogenesis is a common feature of bone erosion, notably in osteoporosis but also in inflammatory diseases such as rheumatoid arthritis (RA) and osteoarticular infections. Human cytomegalovirus (HCMV) infection has been described to impair monocyte differentiation into macrophages and dendritic
Jiao Du et al.
Journal of cellular and molecular medicine, 24(24), 14231-14246 (2020-11-01)
Acute coronary syndrome caused by the rupture of atherosclerotic plaques is one of the primary causes of cerebrovascular and cardiovascular events. Neovascularization within the plaque is closely associated with its stability. Long non-coding RNA (lncRNA) serves a crucial role in
Kai Li et al.
Cell death & disease, 10(10), 699-699 (2019-09-22)
Spermatogenesis is the complex process of male germline development and requires coordinated interactions by multiple gene products that undergo strict developmental regulations. Increasing evidence has suggested that a number of long noncoding RNAs (lncRNAs) may function as important regulatory molecules
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