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Safety Information

AB9702

Sigma-Aldrich

Anti-Tyrosine Hydroxylase Antibody

Chemicon®, from chicken

Synonym(s):

TH

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

chicken

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, mouse

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgY

NCBI accession no.

NM_000360.3
NM_199292.2
NM_199293.2

UniProt accession no.

P07101

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... TH(7054)

Specificity

Recognizes Tyrosine Hydroxylase

Immunogen

Synthetic peptides from human/mouse Tyrosine Hydroxylase

Application

Anti-Tyrosine Hydroxylase Antibody is an antibody against Tyrosine Hydroxylase for use in IC, IH & WB.
Immunohistochemistry: 1:1000-1:2000 using 2% paraformaldehyde fixed tissues.
Immunocytochemistry: 1:1000-1:2000 using 2% paraformaldehyde fixed cells.
Western Blotting: 1:2000-1:5000

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Neuronal & Glial Markers

Physical form

Affinity purified chicken IgY. Two different antibodies were combined to make this product. Liquid in PBS, pH 7.2 with 0.02% sodium azide.

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

AB9702:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Thomas Andreska et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(33), 6289-6308 (2020-07-12)
Motor learning depends on synaptic plasticity between corticostriatal projections and striatal medium spiny neurons. Retrograde tracing from the dorsolateral striatum reveals that both layer II/III and V neurons in the motor cortex express BDNF as a potential regulator of plasticity
Antonella Meloni et al.
The Journal of clinical endocrinology and metabolism, 104(1), 150-162 (2018-10-20)
In autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), autoantibodies (AutoAbs) labeling brain neurons were reported; conversely, brain MRI alterations associated with these AutoAbs were never reported. To describe brain alterations in APECED and to correlate them with AutoAbs against glutamic acid decarboxylase (GAD)
Ryan M Grippo et al.
Current biology : CB, 27(16), 2465-2475 (2017-08-07)
Dopamine (DA) neurotransmission controls behaviors important for survival, including voluntary movement, reward processing, and detection of salient events, such as food or mate availability. Dopaminergic tone also influences circadian physiology and behavior. Although the evolutionary significance of this input is
Ying Cao et al.
Protein & cell, 9(6), 527-539 (2018-03-29)
Sympathetic arborizations act as the essential efferent signals in regulating the metabolism of peripheral organs including white adipose tissues (WAT). However, whether these local neural structures would be of plastic nature, and how such plasticity might participate in specific metabolic
Weizhao Chen et al.
eLife, 11 (2022-05-11)
Lineage reprogramming of resident glial cells to dopaminergic neurons (DAns) is an attractive prospect of the cell-replacement therapy for Parkinson's disease (PD). However, it is unclear whether repressing polypyrimidine tract binding protein 1 (PTBP1) could efficiently convert astrocyte to DAns
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