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8.51212

Sigma-Aldrich

K-Oxyma Pure

Novabiochem®

Synonym(s):

K-Oxyma Pure, (Z)-ethyl 2-cyano-3-hydroxyacrylate potassium salt

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About This Item

Empirical Formula (Hill Notation):
C5H5KN2O3
CAS Number:
Molecular Weight:
180.20
MDL number:
UNSPSC Code:
12352107
NACRES:
NA.22

Quality Level

product line

Novabiochem®

form

powder

reaction suitability

reaction type: Coupling Reactions

manufacturer/tradename

Novabiochem®

mp

145-155 °C

application(s)

peptide synthesis

storage temp.

2-8°C

General description

A version of Oxyma Pure with improved solubility in DMF, This potassium salt when used in conjunction with DIPCDI does not cause premature cleavage of peptides from the hyperacid-sensitive 2-chlorotrityl resin [1].

Literature references

[1] P. Cherkupally, et al. (2013) Eur. J. Org. Chem., 6372.

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Melting range (lower value): ≥ 145 °C
Melting range (upper value): ≤ 155 °C
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Water (K. F.): ≤ 2.0 %
Identity (Potassium): passes test

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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