8.06538

Sodium methylate

for synthesis

• Synonym(s): Sodium methylate, Sodium methoxide, Sodium methanolate
• Empirical Formula (Hill Notation): CH₃NaO
• CAS Number: 124-41-4
• Molecular Weight: 54.02
• MDL number: MFCD00012179
• UNSPSC Code: 12352107
• EC Index Number: 204-699-5
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: ≥97.0% (acidimetric)
• form: powder
• autoignition temp.: 240 °C
• potency: 2037 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rat)
• mp: 127 °C (decomposition)
• density: 1.3 g/cm³ at 20 °C
• bulk density: 500‑600 kg/m³
• storage temp.: 2-8°C
• InChI: 1S/CH3O.Na/c1-2;/h1H3;/q-1;+1
• InChI key: WQDUMFSSJAZKTM-UHFFFAOYSA-N

Description

Application

• Synthesis and Biological Evaluations: A study on the cyclization of berberine and magnolol with metformin in the presence of sodium methylate, exploring pharmaceutical applications. (Cao et al., 2017).
• Synthesis of 5-Acetyl Derivatives of Alkyl 2-Furoates: This research focuses on the synthesis of acetyl derivatives using sodium methylate, demonstrating its role in organic synthesis. (Kuticheva et al., 2015).

Analysis Note

Assay (acidimetric): ≥ 97.0 %
Assay (NaOH): ≤ 1.0 %

Safety Information

• Pictograms: GHS02,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H228 - H251 - H290 - H302 - H314
• Precautionary Statements: P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Flam. Sol. 1 - Met. Corr. 1 - Self-heat. 1 - Skin Corr. 1A
• Supplementary Hazards: EUH014
• Storage Class Code: 4.2 - Pyrophoric and self-heating hazardous materials
• WGK: WGK 2
• Flash Point(F): 91.4 °F - closed cup
• Flash Point(C): 33 °C - closed cup