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Key Documents

Safety Information

6.06044

Sigma-Aldrich

Dichloromethane

for chromatography

Synonym(s):

Dichloromethane, Methylene chloride

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About This Item

Empirical Formula (Hill Notation):
CH2Cl2
CAS Number:
Molecular Weight:
84.93
Beilstein:
1730800
MDL number:
UNSPSC Code:
12352101

grade

for chromatography

Quality Level

vapor density

2.9 (vs air)

vapor pressure

24.45 psi ( 55 °C)
6.83 psi ( 20 °C)

autoignition temp.

1223 °F

expl. lim.

22 %

refractive index

n20/D 1.424 (lit.)

bp

39.8-40 °C (lit.)

mp

−95 °C (lit.)

density

1.325 g/mL at 25 °C (lit.)

SMILES string

ClCCl

InChI

1S/CH2Cl2/c2-1-3/h1H2

InChI key

YMWUJEATGCHHMB-UHFFFAOYSA-N

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General description

Dichloromethane is commonly used as a mobile phase solvent in liquid chromatography (LC).

Application

Dichloromethane can be used as:
  • A mobile phase component in LC-APPI-MS analysis of six TAG (Triacylglycero) model compounds by non-aqueous reversed-phase chromatography.
  • An eluent in the analysis of sulforaphane.

Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 2

Flash Point(F)

does not flash

Flash Point(C)

does not flash


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Class I Designated Chemical Substances

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

IN26060442501:
IN26060441000:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Determination of sulforaphane in broccoli and cabbage by high-performance liquid chromatography
Liang H, et al.
Journal of food composition and analysis, 9(5), 473-476 (2006)
Liquid chromatography--atmospheric pressure photoionization-mass spectrometry analysis of triacylglycerol lipids?Effects of mobile phases on sensitivity
Cai SS, et al.
Journal of Chromatography A, 1173(1-2), 88-97 (2007)
Enhanced extraction yields and mobile phase separations by solvent mixtures for the analysis of metabolites in Annona muricata L. leaves
Ribeiro de Souza EB, et al.
Journal of Separation Science, 32(23-24), 4176-4185 (2009)
Stationary and mobile phases in hydrophilic interaction chromatography: a review
Jandera, Pavel
Analytica Chimica Acta, 692(1-2), 1-25 (2011)

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