580217

Taurocholic Acid, Sodium Salt

Detergent useful for the solubilization of lipids and membrane-bound proteins. Aggregation number: 4.

• Synonym(s): Taurocholic Acid, Sodium Salt, Sodium Taurocholate
• Empirical Formula (Hill Notation): C₂₆H₄₄NO₇S · Na
• CAS Number: 145-42-6
• Molecular Weight: 537.68
• MDL number: MFCD00013050
• UNSPSC Code: 12352106
• NACRES: NA.21

Properties

• Quality Level: 100
• Assay: ≥90% (TLC)
• form: solid
• mol wt: micellar wt 2100
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic)
• aggregation number: 4
• color: white
• pKa: 1.9
• CMC: 3 - 11 mM
• solubility: water: soluble
• shipped in: ambient
• storage temp.: 2-8°C
• InChI: 1S/C26H45NO7S.Na/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);/q;+1/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;/m1./s1
• InChI key: JAJWGJBVLPIOOH-IZYKLYLVSA-M

Description

General description

Detergent useful for the solubilization of lipids and membrane–bound proteins. Aggregation number: 4.

Detergent useful for the solubilization of lipids and membrane-bound proteins (aggregation number: 4; CMC: 3-11 mM; micellar weight: 2100; pK_a: 1.9).

Application

• Discovery of Taurocholic Acid Sodium Hydrate as a Novel Repurposing Drug for Intervertebral Disc Degeneration by Targeting MAPK3.: This research highlights the therapeutic potential of taurocholic acid, sodium salt in treating intervertebral disc degeneration. By targeting the MAPK3 pathway, it offers a new approach to managing spinal disorders, reflecting its significance in developing innovative treatments (Li P et al., 2024).


• Effects of extraction methods and particle size distribution on the structural, physicochemical, and functional properties of dietary fiber from deoiled cumin.: This research uses taurocholic acid, sodium salt to investigate the optimization of dietary fiber extraction, contributing to advancements in food chemistry and health-related product development (Ma MM et al., 2016).

Warning

Toxicity: Standard Handling (A)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable