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Safety Information

345812

Millipore

G 418 Sulfate, Sterile-Filtered Aqueous Solution, Cell Culture Tested - CAS 108321-42-2 - Calbiochem

Synonym(s):

G 418 Sulfate, Sterile-Filtered Aqueous Solution, Cell Culture Tested - CAS 108321-42-2 - Calbiochem, G418, G 418, NMD Inhibitor I

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About This Item

Empirical Formula (Hill Notation):
C20H40N4O10 · 2H2SO4
CAS Number:
108321-42-2
Molecular Weight:
692.71
MDL number:
MFCD00058314
UNSPSC Code:
12352200

Assay

≥98% (TLC)

Quality Level

100

form

solution

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

clear colorless

shipped in

ambient

storage temp.

2-8°C

SMILES string

[S](=O)(=O)(O)O.N([C@@H]1[C@H]([C@H](OC[C@@]1(O)C)O[C@@H]2[C@H]([C@@H]([C@H](C[C@H]2N)N)O[C@H]3O[C@@H]([C@H]([C@@H]([C@H]3N)O)O)[C@H](O)C)O)O)C

InChI key

QNQZPJLBGRQFDD-ZMSORURPSA-N

General description

Aminoglycoside related to gentamycin. Widely used in the selection of eukaryotic expression vectors. Toxic to both prokaryotic and eukaryotic cells. Liquid formulation of Cat. No. 345810.
Sterile-filtered solution of Cat. No. 345810.

Biochem/physiol Actions

Potency: ≥730 µg/mg

Warning

Toxicity: Standard Handling (A)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Geneticin is a registered trademark of Gibco BRL Life Technologies, Inc.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

345812-10ML:
345812-ML:
345812-20ML:
345812-50ML:
345812-100ML:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Harsh Nagpal et al.
Nature communications, 14(1), 8227-8227 (2023-12-13)
Centromeres are epigenetically defined via the presence of the histone H3 variant CENP-A. Contacting CENP-A nucleosomes, the constitutive centromere associated network (CCAN) and the kinetochore assemble, connecting the centromere to spindle microtubules during cell division. The DNA-binding centromeric protein CENP-B
Darrell Pilling et al.
Respiratory research, 23(1), 215-215 (2022-08-24)
Sialic acid is often the distal sugar on glycoconjugates, and sialidases are enzymes that remove this sugar. In fibrotic lesions in human and mouse lungs, there is extensive desialylation of glycoconjugates, and upregulation of sialidases including the extracellular sialidase NEU3.
Rega H Kasim et al.
Frontiers in medical technology, 6, 1407409-1407409 (2024-07-29)
Ghrelin is an orexigenic peptide that becomes post-translationally modified. Natural autoantibodies to ghrelin (ghrelin-aAb) have been described in healthy subjects, in eating disorders and rheumatic diseases, with potential clinical relevance. Despite these important reports, the data base on the prevalence
Shunsuke Kawasaki et al.
Nature communications, 14(1), 2243-2243 (2023-04-20)
Translational modulation based on RNA-binding proteins can be used to construct artificial gene circuits, but RNA-binding proteins capable of regulating translation efficiently and orthogonally remain scarce. Here we report CARTRIDGE (Cas-Responsive Translational Regulation Integratable into Diverse Gene control) to repurpose
Yu Kaku et al.
Cell reports, 36(2), 109385-109385 (2021-07-09)
Administration of convalescent plasma or neutralizing monoclonal antibodies (mAbs) is a potent therapeutic option for coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, SARS-CoV-2 variants with mutations in the spike protein have emerged
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