Skip to Content
Merck
All Photos(1)

Documents

Safety Information

330200-M

Sigma-Aldrich

Ecotin, E. coli

A potent, broad range inhibitor of serine proteases.

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥90% (SDS-PAGE)

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

storage temp.

−70°C

General description

A potent, broad range inhibitor of serine proteases.
A potent, broad range inhibitor of serine proteases. Exhibits picomolar binding constant for the inhibition of chymotrypsin, elastase, Factor Xa, Factor XIIa, kallikrein, and trypsin. Also acts as an effective inhibitor of collagenase.
A potent, broad range inhibitor or serine proteases. Exhibits picomolar binding constant for the inhibition of chymotrypsin, elastase, Factor Xa, Factor XIIa, kallikrein, and trypsin. Also an effective inhibitor of collagenase and granzyme B.

Biochem/physiol Actions

Primary Target
serine proteases
Product does not compete with ATP.
Target IC50: 1 pM against serine proteases
binds trypsin in the picomolar range

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In 1.0 mM HCl.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Other Notes

McGrath, M.E., et al. 1995. Protein Sci. 4, 141.
Seong, I.S., et al. 1994. J. Biol. Chem. 269, 21915.
McGrath, M.E., et al. 1991. J. Biol. Chem. 266, 6620.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

330200-UG:
330200-100UG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service