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Safety Information

1.42002

SAFC

Calcium chloride dihydrate

EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP, FCC, E 509

Pharma Manufacturing

Synonym(s):

Calcium dichloride

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About This Item

Empirical Formula (Hill Notation):
CaCl2 · 2H2O
CAS Number:
Molecular Weight:
147.01
MDL number:
UNSPSC Code:
12352302
E Number:
E509
EC Index Number:
233-140-8

Agency

BP
ChP
JP
Ph. Eur.
USP

Quality Level

reg. compliance

FCC

product line

EMPROVE® EXPERT

form

solid

pH

4.5-8.5 (20 °C, 50 g/L in H2O)

mp

176 °C (dec.) (lit.)

solubility

soluble

application(s)

liquid formulation
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

SMILES string

O.O.Cl[Ca]Cl

InChI

1S/Ca.2ClH.2H2O/h;2*1H;2*1H2/q+2;;;;/p-2

InChI key

LLSDKQJKOVVTOJ-UHFFFAOYSA-L

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Calcium chloride dihydrate is a mineral salt typically used as buffering agent in pharmaceutical formulations. Beyond, calcium chloride dihydrate is used as a complexing builder, flavor enhancer and stabilizer for food and beverage.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

1420025000BWT:
1420020001:
TH11420009525:
CO1I1420029029:
1420029600:
CO1E1420025000:
1420021004:
1420029052:
1420029100:
1420021003:
CO1E1420029029:
1420029029:
CO1I1420025000:
1420029029BWT:
1420029525:
1420029043:
1420025000:
1420029053:
1.42000.1000DISC:
1420029012:
CO1E1420021000:
1420020000:
1420021006:
CO1E1420029525:
1420021000:
1.42000.1000:
1420021005:
1420025002:
1420021000BWT:
1420029999:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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