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Safety Information

1.41351

SAFC

Polyvinyl alcohol

8-88, EMPROVE® ESSENTIAL, Ph. Eur., USP, JPE

Pharma Manufacturing

Synonym(s):

Poly(vinyl alcohol), PVA, PVOH

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About This Item

Linear Formula:
[-CH2CHOH-]n
CAS Number:
9002-89-5
MDL number:
MFCD00081922
UNSPSC Code:
13111042

Agency

JPE
Ph. Eur.
USP

Quality Level

500

product line

EMPROVE® ESSENTIAL

form

scales

mp

160-240 °C

application(s)

controlled release
liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

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General description

When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Polyvinyl alcohol 8-88 is a synthetic, bio-compatible, toxicologically safe, and multi-compendial polymer. It is part of a portfolio spanning a wide range of pharmaceutical grade polyvinyl alcohols of different viscosities, hydrolysis grades and molecular weights and is well suited for a broad variety of pharmaceutical applications, including solid, liquid, and semi-solid formulations.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

CO1E1413511000:
1413510001:
1413511000:
MX11413511000:
1413511000BWT:
1413519025:
1413519029:
1413519028:
1413510000:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Use of PVA to Overcome Challenges in Ophthalmic Formulations

PVA meets all the essential requirements to be used in ophthalmic preparations and offers important benefits compared to HPMC and CMC.

Protocols

Determination of Silver in Water and Wastewater: Photometric Determination Using Phenanthroline Method and Eosin Y

The article describes the sample preparation and photometric determination of silver concentration in water samples using Spectroquant® photometers and test kits.

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