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Key Documents

Safety Information

137666

SAFC

Ethylene Glycol Emprove® Evolve

CIP (cleaning in place)

Pharma Manufacturing

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About This Item

UNSPSC Code:
12352137

Agency

CIP (cleaning in place)

Quality Level

vapor pressure

0.053 hPa ( 20 °C)

Assay

≥99.5% (GC)

form

liquid

autoignition temp.

410 °C

expl. lim.

3.2-15.3 %

impurities

≤0.00002% Chloride (CI)
≤0.001% Acidity (as CH3COOH)

pH

6-7.5 (20 °C, 100 g/L)

bp

197.6 °C/1013 hPa

mp

-14--10 °C

transition temp

flash point 111 °C

density

1.11 g/cm3 at 20 °C

application(s)

pharma/biopharma processes

storage temp.

2-30°C

General description

The new Ehtylene Glycol Emprove® Evolve meets the increasing quality requirements of of the biopharma industry for cleaning and storage of protein A resin.
We offer a range of high quality critical raw materials plus the documentation and expertise to help our customers meet stringent regulatory requirements. Our SAFC® portfolio of high-quality products withstands strict quality control procedures.

Application

Ethylene Glycol EMPROVE® Evolve meets the increasing quality requirements of the biopharma industry for cleaning and storage of protein A resin in downstream processes.
This chemical is used in the downstream process for the cleaning and storage of protein A resin.

Features and Benefits

Ethylene Glycol Emprove® Evolve cleaning and storage chemical can increase the lifetime of our Eshmuno® A resin as well as other protein A resins.

Packaging

Packsizes:
  • 1376661000: 1 L
  • 1376669025: 25 L
  • 1376669950: 950 L

Other Notes

More than 100% increase in column lifetime was achieved using a mixture of 20 % Ethylene Glycol and 0.1M NaOH solution. As a comparison, using traditional 0.1M solution resulted in an 80 % drop after just 250 cycles compared to an impressive 600 cycles using Ethylene Glycol Emprove® Evolve and 0.1M NaOH solution.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation markHealth hazard

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - STOT RE 2 Oral

Target Organs

Kidney

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

239.0 °F - open cup

Flash Point(C)

115 °C - open cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Flammable liquids
Type 3 petroleums
Hazardous rank III
Water soluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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