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Safety Information

12-523

Sigma-Aldrich

GST, 6 His-tagged

Synonym(s):

GST Fusion Protein

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About This Item

UNSPSC Code:
12352204
eCl@ss:
32160405
NACRES:
NA.41

form

liquid

Quality Level

100

manufacturer/tradename

Upstate®

technique(s)

affinity chromatography: suitable

NCBI accession no.

NM_000852.2

UniProt accession no.

P09211

shipped in

dry ice

General description

Glutathione S-transferase (GST) belongs to three families of proteins distinguished as cytosolic, mitochondrial, and microsomal GST. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: α, κ, μ, ω, π, σ, θ, and ζ. This product is a C-terminal 6 histidine-tagged, recombinant full-length glutathione S-transferase (GST).

Biochem/physiol Actions

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in phase II detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

Physical form

50mM Tris-HCl, pH 8, 150mM NaCl, 20% glycerol

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

12-523:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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