1.08879

Zinc sulfate solution

c(ZnSO₄) = 0.1 mol/l, reag. Ph. Eur., reag. USP, ready-to-use volumetric solution for titration, Titriplex^®

• UNSPSC Code: 12352302
• NACRES: NA.21

Properties

• product name: Zinc sulfate solution, c(ZnSO₄) = 0.1 mol/l, Titripur^®, reag. Ph. Eur., reag. USP
• Agency: reag. Ph. Eur.; reag. USP
• Quality Level: 200
• product line: Titripur^®
• form: liquid
• quality: Analyzed in our ISO 17025 accredited QC lab
• reaction suitability: reaction type: Redox Reactions
• concentration: 0.1 M
• technique(s): titration: suitable
• pH: 4.8 (20 °C in H₂O)
• density: 1.02 g/m³ at 20 °C
• storage temp.: 15-25°C

Description

Application

• Quantitation of Mycophenolic Acid and Mycophenolic Acid Glucuronide in Serum or Plasma by LC-MS/MS.: This study demonstrates a liquid chromatography-mass spectrometry method using zinc sulfate solution as part of the sample preparation process. The method allows precise quantification of immunosuppressive drugs, enhancing therapeutic drug monitoring and clinical outcomes (Garg et al., 2023).


• Targeted profiling of 24 sulfated and non-sulfated bile acids in urine using two-dimensional isotope dilution UHPLC-MS/MS.: Zinc sulfate solution is employed in this advanced analytical technique to enhance the detection and quantification of bile acids in urine. This application is crucial for diagnosing and monitoring liver and gastrointestinal diseases (Habler et al., 2022).


• Rapid detection method of carbapenemase-producing Enterobacteriaceae by MALDI-TOF MS with imipenem/cilastatin (KB) disc and zinc sulfate solution.: This research utilizes zinc sulfate solution to improve the rapid detection of antibiotic resistance in bacteria via mass spectrometry, crucial for timely and effective treatment of infections (Oho et al., 2021).

Features and Benefits

Accreditation:
This volumetric solution is analyzed by our calibration laboratory D-K-15185-01-00 which is accredited according to DIN EN ISO/IEC 17025 for analysis of amount-of-substance concentrations in volumetric solutions by DAkkS (Deutsche Akkreditierungsstelle - German National Accreditation Body). The accreditation certificate can be found at www.sigmaaldrich.com/ISO17025.

Packaging

SKU-pack size numbers ending with a "3" are SmartChemicals with an RFID tag on the label for seamless data transfer to the instrument, e.g. xxxxxx1003 or xxxxxxx 4003. More information on www.sigmaaldrich.com/SmartChemicals

Analysis Note

Form liquid
Amount-of-substance concentration 0.0995 - 0.1005 mol/L
Measurement uncertainty ± 0.0003 mol/L
Traceability NIST SRM

The concentration is determined by volumetric titration and refers to 20°C.
The amount-of-substance concentration of this volumetric solution is determined with standardized titriplex-III solution (article number 1.08431). The titriplex-III solution is standardized and traceable to a primary standard reference material (SRM) from the National Institute of Standards and Technology, Gaithersburg, USA (NIST SRM 682 Zinc) by means of volumetric standard Zinc (article number 1.02409), certified reference material according to ISO 17034, analyzed by our accredited calibration laboratory of Merck KGaA, Darmstadt, Germany according to DIN EN ISO/IEC 17025. The uncertainty is expressed as expanded measurement uncertainty with a coverage factor k=2 covering a confidence level of 95%.

Note: The titer is a correction factor to correct for variations of the volumetric solution, the titration equipment, the temperature and other laboratory conditions. For correct titration results it is recommended to determine a titer with the laboratory specific equipment and under laboratory specific conditions directly after opening a new bottle and at regular time intervals.

Legal Information

Titripur is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319 - H412
• Precautionary Statements: P264 - P273 - P280 - P305 + P351 + P338 - P337 + P313 - P501
• Hazard Classifications: Aquatic Chronic 3 - Eye Irrit. 2
• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable