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Safety Information

1.04852

SAFC

Potassium hydrogen carbonate

EMPROVE® ESSENTIAL, Ph. Eur., BP, USP, FCC, E 501

Pharma Manufacturing

Synonym(s):

Potassium hydrogen carbonate, Potassium bicarbonate

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About This Item

Empirical Formula (Hill Notation):
CHKO3
CAS Number:
298-14-6
Molecular Weight:
100.12
MDL number:
MFCD00011402
UNSPSC Code:
12352302
E Number:
E501
EC Index Number:
206-059-0

Agency

BP
Ph. Eur.
USP

Quality Level

500

reg. compliance

FCC

product line

EMPROVE® ESSENTIAL

form

solid

pH

8.4-8.6 (20 °C, 99 g/L in H2O)

solubility

362 g/L

density

2.17 g/cm3 at 20 °C

application(s)

liquid formulation
pharmaceutical
solid formulation

storage temp.

15-25°C

InChI

1S/CH2O3.K/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

InChI key

TYJJADVDDVDEDZ-UHFFFAOYSA-M

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Potassium hydrogen carbonate (synonym potassium bicarbonate) is a commonly used ingredient in both food and pharmaceutics. In pharmaceutical applications, potassium hydrogen carbonate is primarily used as a source of carbon dioxide in oral formulations such as effervescent tablets or granules.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

1048528889:
1048520000:
CO1E1048529029:
1048529010:
1048529028:
1048529500:
1048529999:
1048521000:
CO1E1048521000:
CO1I1048521000:
1048529029BWT:
1048529029:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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