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Safety Information

1.00029

Supelco

Acetonitrile

≥99.9% (GC), suitable for LC/MS, LiChrosolv®

Synonym(s):

ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide

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About This Item

Linear Formula:
CH3CN
CAS Number:
Molecular Weight:
41.05
Beilstein:
741857
MDL number:
UNSPSC Code:
12191502
EC Index Number:
200-835-2
NACRES:
NA.03

product name

Acetonitrile, hypergrade for LC-MS LiChrosolv®

Agency

suitable for ASTM® 7968
suitable for ASTM® 7979
suitable for DIN 38407-42
suitable for EPA 1633
suitable for EPA 8327
suitable for GB 31604.35-2016
suitable for GB 5009.253-2016
suitable for ISO 21675 2019

Quality Level

reg. compliance

suitable for FDA C-010.02

vapor density

1.41 (vs air)

vapor pressure

72.8 mmHg ( 20 °C)
97 hPa ( 20 °C)

product line

LiChrosolv®

Assay

≥99.9% (GC)

form

liquid

autoignition temp.

524 °C
973 °F

expl. lim.

16 %

technique(s)

LC/MS: suitable

impurities

≤0.0001 meq/g Acidity
≤0.0002 meq/g Alkalinity
≤0.01% Water
≤10 ppb Al (Aluminium)
≤10 ppb Ca (Calcium)
≤10 ppb Fe (Iron)
≤10 ppb Mg (Magnesium)
≤5 ppb Any further metal (ICP-MS)
≤5 ppb K (Potassium)
≤50 ppb Na (Sodium)

evapn. residue

≤1.0 mg/L

color

APHA: ≤10

transmittance

191 nm, ≥25%
195 nm, ≥85%
200 nm, ≥96%
215 nm, ≥98%
230 nm, ≥99%

refractive index

n20/D 1.344 (lit.)

bp

81-82 °C (lit.)

mp

−45 °C (lit.)

SMILES string

CC#N

transition temp

flash point 2 °C

density

0.786 g/mL at 25 °C (lit.)

format

neat

storage temp.

2-30°C

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

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General description

LiChrosolv hypergrade is accurately tested for LC-MS suitability, and meet all the requirements of modern LC-MS ionization methods (ESI/APCI - positive and negative mode). Thanks to their low level of ionic background and low ion suppression, LiChrosolv hypergrade solvents provide high reproducibility and high ionization efficiency. The packaging material has been improved to meet LC-MS quality requirements perfectly.

Application

Acetonitrile is used as a component:
  • Of the mobile phase in fast LC-MS quantification of illudane glycosides and analogs in bracken ferns.
  • In the elution mixture to extract (fluoro)quinolone antibiotic compounds from the SDB-RPS extraction cartridge.

Preparation Note

Product filtered through a 0.2 μm filter

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

ASTM is a registered trademark of American Society for Testing and Materials
LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2.0 °C - closed cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water soluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

JP11000291000:
1000299031:
1000290000:
1000294000:
100029-BULK:
1000299030:
1000299010:
1000292508:
1000299187:
1000292500:4548174002902
1000299185:
1000291000:4548174002896
1000298891:
1000294008:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fast LC-MS quantification of ptesculentoside, caudatoside, ptaquiloside and corresponding pterosins in bracken ferns
Vaidotas K et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1138, 121966-121966 (2020)
Determination of (fluoro) quinolone antibiotic residues in pig kidney using liquid chromatography-tandem mass spectrometry: I. Laboratory-validated method.
Brigitte T, et al.
Journal of Chromatography A, 1088, 32-39 (2005)

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