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Safety Information

07-916

Sigma-Aldrich

Anti-Rap1 Antibody

Upstate®, from rabbit

Synonym(s):

Anti-GDS1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat, mouse, human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... RAP1GDS1(5910)

Specificity

Recognizes recombinant human Rap1a and Rap1b proteins

Immunogen

KLH-conjugated, synthetic peptide (KYDPTIEDSYRKQVEVDC) corresponding to amino acids 31-48 human Rap1a.

Application

Research Category
Signaling
Research Sub Category
G-proteins
This Anti-Rap1 Antibody is validated for use in WB for the detection of Rap1.

Quality

Routinely evaluated by immunoblot and affinity precipitation assay.

Target description

22 kDa

Physical form

ImmunoAffinity Purified
Purified rabbit polyclonal in 0.02M phosphate buffer, pH 7.6, 0.25M NaCl, and 0.1% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

07-916:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Annette Artz et al.
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Growth differentiation factor 15 (GDF-15) is the first cytokine known to counteract chemokine-induced activation of leukocyte integrins. We showed recently that this activity dampens neutrophil recruitment into inflamed tissue and is required for survival of myocardial infarction in mice. The
Danielle J Huk et al.
Thyroid : official journal of the American Thyroid Association, 28(9), 1153-1161 (2018-06-09)
Thyroid cancer is an emerging health problem in the United States and worldwide. With incidence rates of thyroid cancer rapidly rising, the need to develop new treatment options is becoming a priority, and understanding the molecular mechanisms of this disease
The coreceptor programmed death 1 inhibits T-cell adhesion by regulating Rap1.
Inbar Azoulay-Alfaguter et al.
The Journal of allergy and clinical immunology, 135(2), 564-567 (2014-09-23)
Seema Shah et al.
Neoplasia (New York, N.Y.), 20(9), 951-963 (2018-08-26)
Diagnosis of breast ductal carcinoma in situ (DCIS) presents a challenge since we cannot yet distinguish those cases that would remain indolent and not require aggressive treatment from cases that may progress to invasive ductal cancer (IDC). The purpose of
Deepak P Srivastava et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(34), 11864-11878 (2012-08-24)
Deficits in social and communication behaviors are common features of a number of neurodevelopmental disorders. However, the molecular and cellular substrates of these higher order brain functions are not well understood. Here we report that specific alterations in social and

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