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Safety Information

L-002

Supelco

LSD-D3 solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

Lysergic acid diethylamide-D3

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About This Item

Empirical Formula (Hill Notation):
C20H22N3OD3
CAS Number:
Molecular Weight:
326.45
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule D (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

concentration

100 μg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

2-8°C

SMILES string

O=C(N(CC)CC)[C@H]1CN(C([2H])([2H])[2H])[C@](C2=C1)([H])CC3=CNC4=C3C2=CC=C4

InChI

1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1/i3D3

InChI key

VAYOSLLFUXYJDT-WABLSUFGSA-N

General description

LSD, or lysergic acid diethylamide, is an illicit psychedelic drug with potent hallucinogenic effects such as altered thinking processes, closed- and open-eye visuals, synesthesia and an altered sense of time. This internal standard is suitable for LSD testing or isotope dilution methods by GC/MS or LC/MS for urine drug testing, clinical toxicology, or forensic analysis.

Application


  • Hydrocodone-D₃ Analytical Standard Applications: Hydrocodone-D₃ serves as a crucial analytical standard in forensic toxicology, enabling precise quantification and validation of hydrocoDonein biological samples. Its stable isotope-labeled structure is essential for mass spectrometry, providing accurate measurement standards for opioid research and ensuring reliability in legal and clinical settings (Gent et al., 2024).

  • Role in Opioid Research: The compound is instrumental in opioid research, particularly in studying hydrocodone′s pharmacokinetics and dynamics. As a deuterated internal standard, Hydrocodone-D₃ enhances the specificity and sensitivity of assays designed to investigate opioid metabolism and its interactions within the human body (Upadhyay et al., 2024).

  • Biotech Research Chemical Standard: In biotechnology, Hydrocodone-D₃ is used for developing new drug formulations and therapeutic approaches. Its application extends to creating more effective opioid medications with controlled release properties, aimed at reducing dependency and side effects (Senta et al., 2020).

  • Pharmacokinetic Studies: This solution is pivotal in pharmacokinetic studies where researchers assess the absorption, distribution, metabolism, and excretion (ADME) of hydrocodone. By using Hydrocodone-D₃, scientists can track and understand the drug′s behavior in the body more accurately, leading to improved dosing guidelines and safer drug use (Dias Neves et al., 2024).

  • Advancements in Bioanalysis: Hydrocodone-D₃ is also used in advanced bioanalytical research to explore new methodologies for drug testing and monitoring. It acts as a reference point in developing novel detection techniques that are crucial for clinical diagnostics and therapeutic drug monitoring (Zhuang et al., 2024).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2 °C - closed cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

L-002-CC:
L-002-1ML:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Justyna McIntyre et al.
The Journal of biological chemistry, 290(45), 27332-27344 (2015-09-16)
Human DNA polymerases (pols) η and ι are Y-family DNA polymerase paralogs that facilitate translesion synthesis past damaged DNA. Both polη and polι can be monoubiquitinated in vivo. Polη has been shown to be ubiquitinated at one primary site. When

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