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Safety Information

I-034

Supelco

Human Insulin solution

100 μg/mL in PBS, pH 7.2, certified reference material, ampule of 100 μL, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C257H383N65O77S6
CAS Number:
Molecular Weight:
5807.57
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 100 μL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in PBS, pH 7.2

technique(s)

liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

InChI key

PBGKTOXHQIOBKM-FHFVDXKLSA-N

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General description

Human insulin is a peptide hormone, composed of 51 amino acids, produced by beta cells of the pancreatic islets. Insulin regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of, especially glucose from the blood into liver, fat and skeletal muscle cells. Insulin levels are routinely measured to evaluate insulin production; diagnose insulin-producing tumors; determine hypoglycemia or to identify insulin resistance. This certified Snap-N-Spike® solution of the fully-intact human insulin protein is suitable for use as starting material in calibrators and controls in LC-MS/MS insulin testing methods.
The Recombinant Human Insulin in phosphate buffered saline (PBS), pH 7.2 (solution) is a standard that fulfills the criteria set by ISO for a certified reference material and a primary standard. It is traceable to the SI and higher order standards through a continuous series of comparisons.

Application

Human Insulin solution is suitable for the in vitro identification, calibration, and quantification of the analyte(s) in analytical and R&D applications.

Features and Benefits

  • The active insulin content is determined through quantitative amino acid analysis (AAA) and chromatographic purity.
  • Each raw material used in the standard has undergone identification and thorough characterization using multiple analytical techniques.
  • A Mass Balance Purity Factor is assigned to each raw material.
  • The standard is prepared using balances that are fully qualified and calibrated to meet ISO 17025 requirements.
  • The standard is prepared and certified under the ISO 17034, ISO/IEC 17025, ISO 9001, and ISO 13485 standards.

Preparation Note

  • Thaw the product at refrigerator or room temperature.
  • Mix well before use.
  • Once thawed, do not refreeze the product.
  • Use established good laboratory practices to quantitatively transfer the desired volume and spike the product into a matrix or dilute it to the desired concentration.

Other Notes

This product′s purpose is for testing. THIS PRODUCT IS NOT INTENDED FOR HUMAN OR THERAPEUTIC USE. Please refer to the safety data sheet for specific details regarding any possible hazards and necessary precautions.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

I-034-0.1ML:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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