Skip to Content
Merck
All Photos(1)

Documents

Safety Information

H-047

Supelco

Hydrocodone-D6 solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C18H15NO3D6
CAS Number:
Molecular Weight:
305.40
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

[2H]C([2H])([2H])Oc1ccc2C[C@@H]3[C@@H]4CCC(=O)[C@@H]5Oc1c2[C@]45CCN3C([2H])([2H])[2H]

InChI

1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3,6,11-12,17H,4-5,7-9H2,1-2H3/t11-,12+,17-,18-/m0/s1/i1D3,2D3

InChI key

LLPOLZWFYMWNKH-CWCHNPBGSA-N

Looking for similar products? Visit Product Comparison Guide

General description

This certified Snap-N-Spike® solution is suitable for quantitation of hydrocodone levels or isotope dilution methods by LC/MS or GC/MS for pain prescription monitoring, clinical toxicology, pharmaceutical research, or forensic analysis. Hydrocodone is an opiate drug used as an analgesic to treat pain and as an antitussive for coughing or related conditions. Also known as dihydrocodeinone, it is one of the most common recreationally-abused prescription drugs due to its widespread availability. Common street names include “hydros”, “dones”, “vics”, and “itchies”.

Application


  • Quantitative plasma analysis for opiates: A robust gas chromatography-triple quadrupole mass spectrometry assay was developed for quantifying opiates in human blood samples, including hydrocodone. Hydrocodone-D₆ was utilized as an internal standard, enhancing the accuracy and reliability of drug monitoring in clinical toxicology (Saad et al., 2019).

  • Advanced LC-MS/MS method for opioid analysis: A liquid chromatography-tandem mass spectrometry method was validated for the analysis of hydrocoDoneand its metabolites in human plasma. Hydrocodone-D₆ served as a critical internal standard, facilitating precise quantification and pharmacokinetic studies in pharmaceutical research (Valtier et al., 2013).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Alcohols
Hazardous rank II

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

H-047-CC:
H-047-1ML:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service