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LM4000

Avanti

19:0 Cholesterol ester

Avanti Research™ - A Croda Brand LM4000, (methanol/chloroform/toluene (50:25:25) solution)

Synonym(s):

cholest-5-en-3β-yl nonadecanoate

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About This Item

Empirical Formula (Hill Notation):
C46H82O2
CAS Number:
25605-90-7
Molecular Weight:
667.14
UNSPSC Code:
12352211
NACRES:
NA.25

form

(methanol/chloroform/toluene (50:25:25) solution)

packaging

pkg of 1 × 1 mL (LM4000-1EA)

manufacturer/tradename

Avanti Research™ - A Croda Brand LM4000

concentration

~10 μg/mL (Refer to C of A for lot specific concentration.)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@]12[C@]([C@](CC[C@H](OC(CCCCCCCCCCCCCCCCCC)=O)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC(C)C

General description

19:0 Cholesterol ester is the central core of lipoprotein particles. CE formation is catalyzed by the enzyme lecithin cholesterol acyl transferase (LCAT).

Application

19:0 Cholesterol ester has been used as a quantitative lipid standard to monitor different lipid extract concentrations.

Biochem/physiol Actions

CE hydrolysis mediates reverse cholesterol transport in macrophage foam cells.

Packaging

2 mL Amber Glass Sealed Ampule (LM4000-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Asp. Tox. 1 - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT RE 2 - STOT SE 1 - STOT SE 3

Target Organs

Central nervous system, Eyes, Liver,Kidney

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Class I Designated Chemical Substances

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

LM4000-1EA:4548174018927
LM4000-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mammalian acyl-CoA:cholesterol acyltransferases
Buhman KF, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1529(1), 142-154 (2000)
The critical role of neutral cholesterol ester hydrolase 1 in cholesterol removal from human macrophages.
Igarashi M, et al.
Circulation Research, 107(11), 1387-1395 (2010)
A comprehensive method for lipid profiling by liquid chromatography-ion cyclotron resonance mass spectrometry
Fauland A, et al.
Journal of Lipid Research, 52(12), 2314-2322 (2011)

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