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860682P

Avanti

Lyso GB3-d7 (synthetic)

powder

Synonym(s):

Globotriaosylsphingosine-d7

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About This Item

Empirical Formula (Hill Notation):
C36H60D7NO17
CAS Number:
2315262-44-1
Molecular Weight:
792.96
UNSPSC Code:
12352211
NACRES:
NA.12

Assay

99% (TLC)

form

powder

packaging

package of 1 × 100 μg (860682P-100UG)

manufacturer/tradename

Avanti Research™ - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@H]1[C@H](OC[C@H](N)[C@H](O)/C=C/CCCCCCCCCCC([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@@H]([C@H](O)[C@H]2O)O[C@H]3O[C@H](CO)[C@@H]([C@H](O)[C@H]3O)O)[C@@H]1O

General description

Globotriaosylsphingosine-d7 (Lyso GB3-d7) is a deuterated derivative of globotriaosylsphingosine (Lyso-GB3). Lyso GB3 is a bioactive glycolipid circulating in the blood. It is a deacylated form of globotriaosylceramide.

Biochem/physiol Actions

Globotriaosylsphingosine (Lyso GB3) accumulates to a greater extent in fabry disease.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (860682P-100UG)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

860682P-BULK:
860682P-100UG:
860682P-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Glucosylsphingosine ≥98.0% (TLC)

Sigma-Aldrich

43659

Glucosylsphingosine

The Fabry disease-associated lipid Lyso-Gb3 enhances voltage-gated calcium currents in sensory neurons and causes pain
Choi L, et al.
Neuroscience Letters, 594, 163-168 (2015)
Lyso-Gb3 activates Notch1 in human podocytes
Sanchez N, et al.
Human Molecular Genetics, 24(20), 5720-5732 (2015)

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