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860671P

Avanti

C16 Ceramide (d14:1/16:0)

Avanti Research™ - A Croda Brand, powder

Synonym(s):

N-palmitoyl-D-erythro-sphingosine (C14 base)

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About This Item

Empirical Formula (Hill Notation):
C30H59NO3
CAS Number:
1228440-96-7
Molecular Weight:
481.79
UNSPSC Code:
12352100
NACRES:
NA.25

Assay

99% (TLC)

form

powder

packaging

1 ea of 10 mg (860671P-10mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

deuterated lipids
sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCC

General description

Ceramide is a sphingolipid metabolite. It is composed of sphingosine base linked via amide linkage to a fatty acid.

Biochem/physiol Actions

Ceramide plays a role in cell signaling processes, such as cell cycle arrest and promotes apoptosis. It is also involved in signal transduction processes and insulin resistance. Ceramide also plays a role in cell proliferation, differentiation and inflammatory responses.

Packaging

5 mL Amber Glass Screw Cap Vial

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

860671P-10MG:
860671P-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ceramide and ceramide 1-phosphate in health and disease
Arana L, et al.
Lipids in Health and Disease, 9(1), 15-15 (2010)
Ceramides and skin function
Coderch L, et al.
American Journal of Clinical Dermatology, 4(2), 107-129 (2003)
Ceramide 1-phosphate/ceramide, a switch between life and death
Gomez-Munoz A
Biochimica et Biophysica Acta - Biomembranes, 1758(12), 2049-2056 (2006)
Mutay Aslan et al.
Nutrition and cancer, 1-13 (2020-04-15)
We aimed to investigate the impact of thymoquinone (TQ), on sphingolipid metabolites, ER stress and apoptotic pathways in MCF-7 and HepG2 cancer cells. Antiproliferative effect was exerted in cancer cells via TQ incubation at different doses and durations. Cell viability

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