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Safety Information

850745P

Avanti

14:0 PE

Avanti Research - A Croda Brand

Synonym(s):

1,2-ditetradecanoyl-sn-glycero-3-phosphoethanolamine; DMPE; PE(14:0/14:0); 110632

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About This Item

Empirical Formula (Hill Notation):
C33H66NO8P
CAS Number:
Molecular Weight:
635.85
UNSPSC Code:
51191904
NACRES:
NA.25

description

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (850745P-1g)
pkg of 1 × 200 mg (850745P-200mg)
pkg of 1 × 25 mg (850745P-25mg)
pkg of 1 × 500 mg (850745P-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O

InChI

1S/C33H66NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-32(35)39-29-31(30-41-43(37,38)40-28-27-34)42-33(36)26-24-22-20-18-16-14-12-10-8-6-4-2/h31H,3-30,34H2,1-2H3,(H,37,38)/t31-/m1/s1

InChI key

NEZDNQCXEZDCBI-WJOKGBTCSA-N

General description

Phosphatidylethanolamine (PE) is an abundant phospholipid, found in the cells of mammals.

Application

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE):
  • has been used as a phospholipid (PL) internal standard in hydrophilic interaction liquid chromatography tandem mass spectrometry (HILIC-LC-MS/MS)
  • has been used as an internal lipid standard to correct the reproducibility in matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry (MALDI FT-ICR MS) analysis
  • may be used in proteoliposomes for planar supported lipid bilayer formation
  • may be used as a biotinylated internal standard to measure externalization of aminophospholipids (APLs) using mass spectrometry (MS)

Biochem/physiol Actions

Phosphatidylethanolamine (PE) plays a key role in the activity of respiratory complexes. PE also participates in the initiation of autophagy.

Packaging

20 mL Clear Glass Screw Cap Vial (850745P-1g)
20 mL Clear Glass Screw Cap Vial (850745P-500mg)
5 mL Amber Glass Screw Cap Vial (850745P-200mg)
5 mL Amber Glass Screw Cap Vial (850745P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

850745P-500MG:
850745P-1G:
850745P-BULK:
850745P-VAR:
850745P-25MG:
850745P-200MG:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Alex J B Kreutzberger et al.
Biophysical journal, 115(9), 1755-1761 (2018-10-22)
Intramembrane proteases hydrolyze peptide bonds within the membrane as a regulatory paradigm that is conserved across all forms of cellular life. Many of these enzymes are thought to be oligomeric, and that their resulting quaternary interactions form the basis of
Paulina Perczyk et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183136-183136 (2019-11-22)
Soil fungi play an important role in the environment decomposing dead organic matter and degrading persistent organic pollutants (POP). The presence of hydrophobic POP in the soil and membrane-lytic substances excreted by competing microorganism to the soil solution is the
Tomas Laursen et al.
Science (New York, N.Y.), 354(6314), 890-893 (2016-11-20)
Metabolic highways may be orchestrated by the assembly of sequential enzymes into protein complexes, or metabolons, to facilitate efficient channeling of intermediates and to prevent undesired metabolic cross-talk while maintaining metabolic flexibility. Here we report the isolation of the dynamic
Alwena H Morgan et al.
Nature protocols, 5(12), 1919-1931 (2010-12-04)
Phospholipid-esterified oxylipins include newly described families of bioactive lipids generated by lipoxygenases in immune cells. Until now, assays for their quantitation were not well developed or widely available. Here, we describe a mass spectrometric protocol that enables accurate measurement of
Yaxi Wang et al.
The Journal of cell biology, 219(5) (2020-04-19)
The yeast phosphatidylserine (PtdSer) decarboxylase Psd2 is proposed to engage in a membrane contact site (MCS) for PtdSer decarboxylation to phosphatidylethanolamine (PtdEtn). This proposed MCS harbors Psd2, the Sec14-like phosphatidylinositol transfer protein (PITP) Sfh4, the Stt4 phosphatidylinositol (PtdIns) 4-OH kinase

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