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800730P

Avanti

N-16:0 L-Serine MeEster

N-palmitoyl L-serine methyl ester, powder

Synonym(s):

1-hexadecanoyl-L-serine methyl ester; (S)-methyl-3-hydroxy-2-hexadecanamidopropanoate; (S)-methyl-3-hydroxy-2-palmitamidopropanoate ; 110830

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5 MG
¥36,330

¥36,330


Estimated to ship onMay 01, 2025


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5 MG
¥36,330

About This Item

Empirical Formula (Hill Notation):
C20H39NO4
CAS Number:
Molecular Weight:
357.53
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25

¥36,330


Estimated to ship onMay 01, 2025


Request a Bulk Order

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (800730P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 800730P

lipid type

phosphoglycerides
bioactive lipids

shipped in

dry ice

storage temp.

−20°C

General description

N-palmitoyl-L-serine methyl ester is an amino acid amphiphile.[1] It is synthesized synthetically from N-succinimidyl palmitate, L-serine methyl ester hydrochloride and triethyl amine.[2]

Biochem/physiol Actions

N-palmitoyl-L-serine methyl ester hydrochloride is used for the synthesis of N-palmitoyl-O-phosphocholine serine (PPCS), which is a prime lipid biomarker in Niemann-Pick disease type C1.[2] It is also used for preparation of amino acid based gelators for drug delivery studies.[3]

Packaging

5 mL Amber Glass Screw Cap Vial (800730P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

800730P-VAR:
800730P-5MG:
800730P-BULK:


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D Vollhardt et al.
Physical chemistry chemical physics : PCCP, 21(1), 96-103 (2018-12-07)
The monolayers of N-alkanoyl substituted threonine amphiphiles, similar to those of other N-alkanoyl-substituted amino acid amphiphiles, point to substantial differences in the main characteristics compared to usual amphiphilic monolayers. π-A measurements of the enantiomeric and racemic forms of N-alkanoyl-substituted threonine
N-acyl-O-phosphocholineserines: structures of a novel class of lipids that are biomarkers for Niemann-Pick C1 disease
Sidhu R, et al.
Journal of Lipid Research, 60(8), 1410-1424 (2019)
Special features of monolayer characteristics of N-alkanoyl substituted threonine amphiphiles
Vollhardt D, et al.
Physical Chemistry Chemical Physics, 21(1), 96-103 (2019)
Rohini Sidhu et al.
Journal of lipid research, 60(8), 1410-1424 (2019-06-16)
Niemann-Pick disease type C1 (NPC1) is a fatal, neurodegenerative, cholesterol storage disorder. With new therapeutics in clinical trials, there is an urgency to improve diagnostics and monitor therapeutic efficacy with biomarkers. In this study, we sought to define the structure
Systematic modifications of amino acid-based organogelators for the investigation of structure-property correlations in drug delivery system
Hu B, et al.
International Journal of Pharmaceutics, 547(1-2), 637-647 (2018)

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