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925802

Sigma-Aldrich

Silk fibroin

average mol wt 100 kDa (water soluble)

Synonym(s):

SilMA, Silk fibroin

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About This Item

UNSPSC Code:
12162002
NACRES:
NA.23

mol wt

average mol wt 100 kDa (water soluble)

Quality Level

100

color

white to off-white

pH

6-8 (2% in water, when dissolved in water)

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General description

Silk is a natural polymer composed of two proteins - fibroin and sericin.
Silk fibroin is used in biomedical applications due to its enhanced biocompatibility and biodegradability.

Silk fibroin (SF) demonstrates enhanced strength and stability compared to other common natural polymers due to its unique features including;
  • amphiphilicity
  • hydrophobicity
  • substantial hydrogen bonding
  • intrinsic low viscosity
  • high protein crystallinity by ß-sheet crystals.

Application

SF is a versatile material, that finds itself in multiple types of scaffolds, with extensive uses in inkjet, extrusion-based, laser-assisted, and DLP bioprinting tissue engineering applications.

Packaging

1 g in glass bottle

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

925802-BULK:
925802-1G:
925802-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Xiaohui Zhang et al.
Advanced drug delivery reviews, 61(12), 988-1006 (2009-08-01)
Electrospinning is a versatile technique that enables the development of nanofiber-based biomaterial scaffolds. Scaffolds can be generated that are useful for tissue engineering and regenerative medicine since they mimic the nanoscale properties of certain fibrous components of the native extracellular
Precisely printable and biocompatible silk fibroin bioink for digital light processing 3D printing.
Kim S H, et al.
Nature Communications, 9, 1620-1620 (2018)
Heesun Hong et al.
Biomaterials, 232, 119679-119679 (2019-12-23)
Three-dimensional printing with Digital Lighting Processing (DLP) printer has come into the new wave in the tissue engineering for regenerative medicine. Especially for the clinical application, it needs to develop of bio-ink with biocompatibility, biodegradability and printability. Therefore, we demonstrated
Soon Hee Kim et al.
Nature communications, 9(1), 1620-1620 (2018-04-26)
Although three-dimensional (3D) bioprinting technology has gained much attention in the field of tissue engineering, there are still several significant engineering challenges to overcome, including lack of bioink with biocompatibility and printability. Here, we show a bioink created from silk

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