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923753

Sigma-Aldrich

INVIVO-GEL TGF-β bioink

suitable for 3D bioprinting applications

Synonym(s):

3D bioprinting, 3DBP, ECM

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About This Item

UNSPSC Code:
12162002
NACRES:
NA.23

Quality Level

100

storage temp.

2-8°C

Application

INVIVO-GEL TGF-β bioink is specifically developed and optimized for 3D bioprinting applications. The INVIVO-GEL TGF-β bioink kit includes optimally formulated TGF-mimetic peptide conjugated gelatin-based hydrogel complex packed in syringe for easy dispensing. The kit also includes Gel-linker, which reinforces mechanical stability. A transparent hydrogel forms when contents are properly mixed and exposed to UV light. This bioink is capable of generating mechanically stable 3D structures that can be maintained for days in the culture environment. TGF may promote ECM production, as reported by numerous studies demonstrating the dramatic increase in matrix synthesis and deposition by vascular smooth muscle and endothelial cells when grown on hydrogels with tethered TGF-β.

Components

INVIVO-GEL TGF-β in syringe 5mL x 2
Gel-linker(A) powder 500µL x 1
Gel-linker(B) powder 1µL x 1

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317,H319

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

923753-1EA-PW:
923753-BULK:
923753-VAR:
923753-1EA:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Designing Gelatin Methacryloyl (GelMA)-Based Bioinks for Visible Light Stereolithographic 3D Biofabrication
Kumar H et al.
Macromolecular Bioscience, 11 (2020)
Gelatin methacryloyl and its hydrogels with an exceptional degree of controllability and batch-to-batch consistency
Zhu et al.
Scientific Reports, 9, 6863-6863 (2019)
Synergetic roles of TGF-? signaling in tissue engineering
Lee et al.
Cytokine, 115, 60?63-60?63 (2019)
Shining Xiao et al.
Stem cell reviews and reports, 15(5), 664-679 (2019-06-04)
Gelatin methacrylate (GelMA)-based hydrogels are gaining a great deal of attention as potentially implantable materials in tissue engineering applications because of their biofunctionality and mechanical tenability. Since different natural tissues respond differently to mechanical stresses, an ideal implanted material would
Mengxiang Zhu et al.
Scientific reports, 9(1), 6863-6863 (2019-05-06)
Gelatin methacryloyl (GelMA) is a versatile material for a wide range of bioapplications. There is an intense interest in developing effective chemical strategies to prepare GelMA with a high degree of batch-to-batch consistency and controllability in terms of methacryloyl functionalization
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