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907197

Sigma-Aldrich

1,4-Dinitro-1-imidazole

Synonym(s):

1,4-DNIm, 1,4-Dinitroimidazole, Bifunctional bioconjugation reagent

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About This Item

Empirical Formula (Hill Notation):
C3H2N4O4
CAS Number:
19182-81-1
Molecular Weight:
158.07
MDL number:
MFCD00297235
UNSPSC Code:
12352005

Assay

≥95%

form

solid

storage temp.

−20°C

InChI

1S/C3H2N4O4/c8-6(9)3-1-5(2-4-3)7(10)11/h1-2H

InChI key

HZPSREFSUPXCMN-UHFFFAOYSA-N

Application

1,4-Dinitro-1-imidazole (1,4-DNIm) and other dinitroimidazoles were demonstrated to be bifunctional bioconjugation reagents for protein functionalization and peptide macrocyclization. In acidic to neutral aqueous conditions, 1,4-DNIms chemoselectively react with cysteines; in organic solvents in the presence of base, 1,4-DNIms chemoselectively react with lysines to form stable conjugates

Other Notes

Dinitroimidazoles as bifunctional bioconjugation reagents for protein functionalization and peptide macrocyclization

related product

Product No.
Description
Pricing

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

907197-VAR:
907197-100MG:
907197-BULK:

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