901699

3-Mercaptopropanyl-N-hydroxysuccinimide ester

>95%

• Synonym(s): NHS ester
• Empirical Formula (Hill Notation): C₇H₉NO₄S
• CAS Number: 117235-10-6
• Molecular Weight: 203.22
• MDL number: MFCD28964889
• UNSPSC Code: 12352005
• NACRES: NA.23

Properties

• Assay: >95%
• form: solid or liquid
• reaction suitability: reagent type: linker
• color: colorless to yellow
• functional group: NHS ester; thiol
• storage temp.: 2-8°C
• SMILES string: SCCC(ON1C(CCC1=O)=O)=O
• InChI: 1S/C7H9NO4S/c9-5-1-2-6(10)8(5)12-7(11)3-4-13/h13H,1-4H2
• InChI key: UTBOEPMMEANMPS-UHFFFAOYSA-N

Description

Application

3-Mercaptopropanyl-N-hydroxysuccinimide ester is an aliphatic, heterobifunctional crosslinking reagent. Due to the functional groups, this material can be used in a multitude of applications, such as the synthesis of protien-polymer conjugates and the synthesis of functionalized quantum dots. In addition to use as a crosslinking agent, this material can also be used to install functional groups post-polymerization. The terminal N-hydroxysuccinimide (NHS) ester can react with amines while the terminal thiol can react with thiols, alkenes, and alkynes. The free thiol can also be used to form self-assembled monolayers (SAMs) on gold surfaces.

3-Mercaptopropanyl-N-hydroxysuccinimide ester can be used in the synthesis of diaminobutane (DAB) based dendrimers for the formation of an ultrafiltration membrane for the removal of heavy metals.

Safety Information

• Pictograms: GHS02
• Signal Word: Warning
• Hazard Statements: H226
• Precautionary Statements: P210 - P233 - P240 - P241 - P242 - P243
• Hazard Classifications: Flam. Liq. 3
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 110.0 °F
• Flash Point(C): 43.33 °C