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901222

Sigma-Aldrich

2-{4-[(Dimethylamino)methyl]-1,2,3-triazol-1-yl}cyclohexan-1-ol

≥95%

Synonym(s):

AMTC

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About This Item

Empirical Formula (Hill Notation):
C11H20N4O
CAS Number:
1817837-32-3
Molecular Weight:
224.30
UNSPSC Code:
12352200
NACRES:
NA.22

Assay

≥95%

form

powder or crystals

reaction suitability

reaction type: click chemistry

mp

81-85 °C

storage temp.

2-8°C

Application

The copper-catalyzed azide-alkyne cycloaddition reaction is a common example of a click chemistry reaction. AMTC can be used as a ligand to the copper to enhance the rate of the reaction. AMTC is water soluble similar to the copper ligand THPTA, but the ligands show different substrate specificities allowing for optimization of reaction conditions. Since AMTC is water soluble it allows for development of applications using biological molecules. After the catalysis of hydrophobic substrates in organic solvents, the aqueous solubility of the ligand allows the option of removal using an aqueous extraction.

Other Notes

A new water-soluble ligand for efficient copper-catalyzed Huisgen cycloaddition of aliphatic azides and alkynes

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

901222-100MG:
901222-BULK:
901222-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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