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900670

Sigma-Aldrich

Poly(ε-caprolactone)-b-poly(ethylene glycol)-b-poly(ε-caprolactone)

2k-2k-2k

Synonym(s):

PCL-PEG-PCL, PCL-PEG-PCL triblock copolymer

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500 MG
¥25,600

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500 MG
¥25,600

About This Item

Linear Formula:
H(OCH2CH2CH2CH2CH2CO)mO(CH2CH2O)n(COCH2CH2CH2CH2CH2O)mH
UNSPSC Code:
12162002
NACRES:
NA.23

¥25,600

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Request a Bulk Order

Quality Level

100

form

powder

transition temp

flash point >230 °F
Tm 49-55 °C

storage temp.

2-8°C

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Application

Biocompatible, amphiphilic triblock polymer composed of a hydrophilic, central PEG block and two terminal hydrophobic PCL blocks. These materials have been used in drug delivery applications as well as thermoplastic elastomers. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Hydroxyl termination allows for facile further chemical modification of these materials.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

900670-500MG:
900670-VAR:
900670-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX2468
MKCT3708
MKCP8092
MKCD0521

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Poly(caprolactone)-poly(ethylene glycol)-poly(caprolactone) (PCL-PEG-PCL) nanoparticles: a valuable and efficient system for in vitro and in vivo delivery of curcumin.
Manjili HK, et al.
Royal Society of Chemistry Advances, 6, 14403-14415 (2016)
ChangYang Gong et al.
International journal of pharmaceutics, 365(1-2), 89-99 (2008-09-17)
In this work, a series of biodegradable triblock poly(ethylene glycol)-poly(epsilon-caprolactone)-poly(ethylene glycol) (PEG-PCL-PEG, PECE) copolymers were successfully synthesized by ring-opening copolymerization, and were characterized by (1)H NMR, FT-IR, GPC, and DSC. Aqueous solutions of PECE copolymers underwent thermosensitive sol-gel-sol transition as
Synthesis and microphase separation of biodegradable poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) multiblock copolymer films.
You JH, et al.
Macromolecular Research, 16(7), 609-613 (2008)
Synthesis and Characterization of PEG-PCL-PEG Triblock Copolymers as Carriers of Doxorubicin for the Treatment of Breast Cancer.
Cuong NV, et al.
Journal of Applied Polymer Science, 117, 3694-3703 (2010)

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