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Safety Information

86020

Sigma-Aldrich

Sulfacetamide sodium salt monohydrate

≥98.0% (dried material, T)

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About This Item

Empirical Formula (Hill Notation):
C8H9N2NaO3S · H2O
CAS Number:
6209-17-2
Molecular Weight:
254.24
MDL number:
MFCD00149555
UNSPSC Code:
12352100
PubChem Substance ID:
57653076

Assay

≥98.0% (dried material, T)

impurities

~7% water

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria
mycoplasma

Mode of action

enzyme | inhibits

SMILES string

NC1=CC=C(S(N([Na])C(C)=O)(=O)=O)C=C1.O

InChI

1S/C8H10N2O3S.Na.H2O/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8;;/h2-5H,9H2,1H3,(H,10,11);;1H2/q;+1;/p-1

InChI key

IHCDKJZZFOUARO-UHFFFAOYSA-M

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General description

Chemical structure: sulfonamide

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

86020-BULK:
86020-500G:
86020-VAR:
86020-100G:

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Certificates of Analysis (COA)

Lot/Batch Number
1393837V
BCBD8932V
BCBD3075V
1393837
440591/1

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Praveen N Naik et al.
Biopharmaceutics & drug disposition, 31(2-3), 120-128 (2010-01-15)
The binding of sulfacetamide sodium (SAS) to bovine serum albumin (BSA) was investigated by spectroscopic methods, namely fluorescence, FT-IR and UV-vis absorption spectral studies. The binding parameters were evaluated by a fluorescence quenching method. The thermodynamic parameters, DeltaH(0), DeltaS(0)and DeltaG(0)
Shmuel Graffi et al.
European journal of ophthalmology, 22(5), 834-835 (2012-01-24)
To report an unusual case of a patient with endogenous endophthalmitis caused by Actinomyces neuii. A 69-year-old woman in an immunosuppressed state and who had a previous history of periappendicular abscess presented with bilateral red painful eyes. The diagnosis was
Demet Sensoy et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 72(3), 487-495 (2009-02-19)
The aim of this study was to prepare bioadhesive sulfacetamide sodium (SA) microspheres to increase their residence time on the ocular surface and to enhance their treatment efficacy on ocular keratitis. Microspheres were fabricated by spray drying method using mixture
Mark W Trumbore et al.
Journal of drugs in dermatology : JDD, 8(3), 299-304 (2009-03-11)
Acne rosacea is a chronic cutaneous disorder affecting as many as 14 million Americans. Papulopustular rosacea is the classic form of rosacea characterized by papules, pustules, and erythema. The skin barrier deficiency and vascular hyperactivity characteristic of papulopustular rosacea increase
Bivash Mandal et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 13(4), 510-523 (2010-01-01)
Polymeric nanosuspension was prepared from an inert polymer resin (Eudragit® RL100) with the aim of improving the availability of sulfacetamide at the intraocular level to combat bacterial infections. Nanosuspensions were prepared by the solvent displacement method using acetone and Pluronic®
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