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Safety Information

744379

Sigma-Aldrich

Trimethylamine

≥99.5%

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About This Item

Linear Formula:
(CH3)3N
CAS Number:
Molecular Weight:
59.11
Beilstein:
956566
EC Number:
MDL number:
UNSPSC Code:
12142100
PubChem Substance ID:
NACRES:
NA.22

vapor density

2.09 (vs air)

vapor pressure

13.3 psi ( 21 °C)

Assay

≥99.5%

form

gas

autoignition temp.

374 °F

expl. lim.

11.6 %

bp

3-4 °C (lit.)

mp

−117 °C (lit.)

density

0.63 g/mL at 20 °C (lit.)

SMILES string

CN(C)C

InChI

1S/C3H9N/c1-4(2)3/h1-3H3

InChI key

GETQZCLCWQTVFV-UHFFFAOYSA-N

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General description

Trimethylamine is a tertiary amine used as a versatile building block in organic synthesis to produce choline chloride, surfactants and solvents, rubber chemicals, tetramethylammonium hydroxide, cationic starches, phase transfer catalysts, ion-exchange resins, and some basic dyes.

Application

Trimethylamine can be used as:
  • A base in dehydrochlorinations, nucleophilic substitutions, 1,4-additions, and aldol-type condensation reactions.
  • A reactant for the preparation of trimethylamine-based dicationic ionic liquids for the extraction of phenolic compounds from oil mixtures.

Packaging

500ml high pressure aluminum cylinder equipped with a stainless steel valve according to DIN 477-1.

Other Notes

For 744379-280G-EU and 744379-280G packaging: 500 mL of aluminium cylinder equipped with stainless steel valve.

Recommended products

For 744379-280G-EU and 744379-280G: outlet fitting: DIN 477-1 no. 1, Z742162 or Z742164 are the recommended regulators.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Gas 1A - Press. Gas Liquefied gas - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

2A - Gases

WGK

WGK 1

Flash Point(F)

19.4 °F - closed cup

Flash Point(C)

-7 °C - closed cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Class I Designated Chemical Substances

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

744379-280G-EU:
744379-280G-BULK:
744379-280G:


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Highly efficient extraction of phenolic compounds from oil mixtures by trimethylamine-based dicationic ionic liquids via forming deep eutectic solvents
Ji Youan, et al.
Fuel Processing Technology, 171(6), 183-191 (2018)
Trimethylamine
Sorgi KL
Encyclopedia of Reagents for Organic Synthesis, Second Edition, 39(6), 501-505 (2007)
Kin Man Au et al.
Science advances, 6(27), eaba8564-eaba8564 (2020-09-15)
Activation of the innate immune system and natural killer (NK) cells has been a key effort in cancer immunotherapy research. Here, we report a nanoparticle-based trispecific NK cell engager (nano-TriNKE) platform that can target epidermal growth factor receptor (EGFR)-overexpressing tumors
Analytical method for monitoring airborne trimethylamine using solid phase micro-extraction and gas chromatography-flame ionization detection
Chien Y-C, et al.
Analytica Chimica Acta, 419(1), 73-79 (2000)
The characteristic fragment ions and visualization of cationic starches on pulp fiber using ToF-SIMS
Matsushita Y, et al.
Surface and Interface Analysis : SIA, 39(6), 501-505 (2007)

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