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Safety Information

743593

Sigma-Aldrich

Ethylene oxide

≥99.9%

Synonym(s):

Oxirane

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About This Item

Empirical Formula (Hill Notation):
C2H4O
CAS Number:
75-21-8
Molecular Weight:
44.05
Beilstein:
102378
EC Number:
200-849-9
MDL number:
MFCD00014482
UNSPSC Code:
12142100
PubChem Substance ID:
329765643
NACRES:
NA.22

Assay

≥99.9%

form

gas

refractive index

n20/D 1.3597 (lit.)

bp

10.7 °C (lit.)

mp

−111 °C (lit.)

density

0.882 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

C1CO1

InChI

1S/C2H4O/c1-2-3-1/h1-2H2

InChI key

IAYPIBMASNFSPL-UHFFFAOYSA-N

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Packaging

500ml high pressure aluminum cylinder equipped with a stainless steel valve according to DIN 477-1.

Other Notes

For 743593-390G-EU packaging: 500 mL of aluminium cylinder equipped with brass valve.

Recommended products

For 743593-390G-EU: outlet fitting: DIN 477-1 no. 1, Z742160 or Z742161 are the recommended regulators.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Chem. Unst. Gas A - Eye Dam. 1 - Flam. Gas 1A - Muta. 1B - Press. Gas Liquefied gas - Repr. 1B - Skin Corr. 1B - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Nervous system, Respiratory system

Storage Class Code

2A - Gases

WGK

WGK 3

Flash Point(F)

-4.0 °F - closed cup

Flash Point(C)

-20.0 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

PRTR

Specified Class I Designated Chemical Substances

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

743593-390G:
743593-390G-BULK:
743593-390G-EU:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Allergy to formaldehyde and ethylene-oxide.
J Bousquet et al.
Clinical reviews in allergy, 9(3-4), 357-370 (1991-01-01)
R Thier et al.
Critical reviews in toxicology, 30(5), 595-608 (2000-10-31)
Long-term inhalation studies in rodents have presented unequivocal evidence of experimental carcinogenicity of ethylene oxide, based on the formation of malignant tumors at multiple sites. However, despite a considerable body of epidemiological data only limited evidence has been obtained of
L Ehrenberg et al.
Mutation research, 330(1-2), 41-54 (1995-08-01)
Data for relationships between in vivo doses inferred from levels of hemoglobin (Hb) or DNA adducts and administered (by inhalation or injection) doses of ethylene oxide (EO) in mice, rats and humans are reviewed. At low absorbed doses or dose
A T Natarajan et al.
Mutation research, 330(1-2), 55-70 (1995-08-01)
A risk estimate of the heritable effects of ethylene oxide exposure, using the parallelogram approach, as suggested by Frits Sobels, is described. The approach is based on available data on the ethylene oxide-induced responses for the same genetic endpoint in
R J Preston
Critical reviews in toxicology, 29(3), 263-282 (1999-06-24)
Cytogenetic assays are an integral component of the battery of short-term assays that are used for the hazard identification component of a cancer risk assessment. The protocol for the conduct of such assays for maximal sensitivity for detecting clastogenicity has
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