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602841

Sigma-Aldrich

Oxygen-17O2

90 atom % 17O

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About This Item

Linear Formula:
17O2
CAS Number:
67321-81-7
Molecular Weight:
34.00
MDL number:
MFCD00084250
UNSPSC Code:
12142200
PubChem Substance ID:
329758853

isotopic purity

90 atom % 17O

Assay

99% (CP)

form

gas

mass shift

M+2

SMILES string

[17O]=[17O]

InChI

1S/O2/c1-2/i1+1,2+1

InChI key

MYMOFIZGZYHOMD-ZDOIIHCHSA-N

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General description

Oxygen-17O2 is the isotopic analogue of oxygen.

Application

Oxygen-17O2 can be used
to estimate the cerebral metabolic rate of oxygen consumption (CMRO2) of swine by detection of metabolically produced H217O by rapid T1-weighted proton magnetic resonance imaging.
to understand the altered cerebral oxygen metabolism in glioma via dynamic 17O MRI.
to measure the quantitative and simultaneous measurement of oxygen consumption rates in rat brain and skeletal muscle using 17O MRS imaging.

Packaging

All gas volumes are quoted at Standard Temperature and Pressure (STP) and not at Normal Temperature and Pressure (NTP). One STP Liter is 7.7% more gas than one NTP Liter.
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Pictograms

Flame over circleGas cylinder
GHS03,GHS04

Signal Word

Danger

Hazard Statements

H270,H280

Hazard Classifications

Ox. Gas 1 - Press. Gas Compr. Gas

Storage Class Code

2A - Gases

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

602841-BULK:
602841-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Eric A Mellon et al.
Journal of neuroscience methods, 179(1), 29-39 (2009-05-12)
Despite the importance of metabolic disturbances in many diseases, there are currently no clinically used methods for the detection of oxidative metabolism in vivo. To address this deficiency, (17)O MRI techniques are scaled from small animals to swine as a
Daniel Paech et al.
Radiology, 295(1), 181-189 (2020-02-19)
Background Altered metabolism is a characteristic of cancer. Because of a shift in glucose metabolism from oxidative phosphorylation to lactate production for energy generation, malignant tumors are characterized by increased glycolysis followed by lactic acid fermentation, even in the presence
Hannes M Wiesner et al.
Magnetic resonance in medicine, 85(4), 2232-2246 (2020-10-27)
Oxygen-17 (17 O) MRS imaging, successfully used in the brain, is extended by imaging the oxygen metabolic rate in the resting skeletal muscle and used to determine the total whole-body oxygen metabolic rate in the rat. During and after inhalations

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