Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Safety Information

530921

Sigma-Aldrich

4-Ethynylpyridine hydrochloride

97%, solid

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C7H5N · HCl
CAS Number:
352530-29-1
Molecular Weight:
139.58
MDL number:
MFCD03093912
UNSPSC Code:
12352100
PubChem Substance ID:
24877786
NACRES:
NA.22

Assay

97%

form

solid

mp

150 °C (dec.) (lit.)

SMILES string

Cl.C#Cc1ccncc1

InChI

1S/C7H5N.ClH/c1-2-7-3-5-8-6-4-7;/h1,3-6H;1H

InChI key

KFBZWZGIZHLUBX-UHFFFAOYSA-N

General description

4-Ethynylpyridine hydrochloride acts as a ligand for the synthesis of various metallic complexes.

Application

4-Ethynylpyridine hydrochloride may be used in the preparation of the following 2-methyl-6-(phenylethynyl)pyridine (MPEP) analogs:
  • 1,4-bis(pyridin-4-ylethynyl)benzene
  • 4-((5,5-dimethyl-1,3,2-dioxaborinan-2-yl)ethynyl)pyridyl
  • 4-((3-iodophenyl)ethynyl)pyridine
  • 4-((4-iodophenyl)ethynyl)pyridine
  • 1,4-di(pyridine-4-yl)buta-1,3-diyne

It may also be used in the preparation of:
  • (rac)-2,8-bis(4-pyridylethynyl)-4,10-dimethyl-5,11-methano-6H,12H-dibenzo[b,f][1,5]diazocine, a Tröger′s base derived bis(pyridyl) ligand
  • (2RS,6RS)-2-(4-methoxyphenyl)-6-(2-(4-(pyridin-4-yl)-1H-1,2,3-triazol-1-yl)ethyl)dihydro-2H-pyran-4(3H)-one, a substituted tetrahydropyrone
  • BINOL (1,1′-bi-2-naphthol)-based bis(4-pyridyl) ligands

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

530921-10G:
530921-VAR:
530921-BULK:
530921-1G:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BGBB9361
BGBB1276V
BGBB0361
1422928
03417TH

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Structural and Nonlinear Optical Properties of Aligned Heterotrinuclear [RuII?(Spacer)?MII?(Spacer)?RuII] Complexes (M= Pd, Pt; spacer= 4?ethynylpyridine).
Ge Q, et al.
Chemistry (Weinheim An Der Bergstrasse, Germany), 4(6), 998-1005 (2009)
Self?Sorting Effects in the Self?Assembly of Metallosupramolecular Rhombi from Chiral BINOL?Derived Bis (pyridine) Ligands.
Gutz C, et al.
European Journal of Organic Chemistry, 2104(1), 206-216 (2014)
Structure?Activity Relationships for Negative Allosteric mGluR5 Modulators.
Kaae BH, et al.
ChemMedChem, 7(3), 440-451 (2012)
Diversity-Oriented Synthesis of a Library of Substituted Tetrahydropyrones Using Oxidative Carbon-Hydrogen Bond Activation and Click Chemistry.
Zaware N, et al.
Molecules (Basel), 16(5), 3648-3662 (2011)
Bis?alkynyl Diruthenium Compounds with Built?in Electronic Asymmetry: Toward an Organometallic Aviram?Ratner Diode.
Ying JW, et al.
Chemistry (Weinheim An Der Bergstrasse, Germany), 13(24), 6874-6882 (2007)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service