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Safety Information

484628

Sigma-Aldrich

Benztropine mesylate

95%

Synonym(s):

Benztropine methanesulfonate

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About This Item

Empirical Formula (Hill Notation):
C21H25NO
CAS Number:
132-17-2
Molecular Weight:
307.43
EC Number:
205-048-8
MDL number:
MFCD00074784
UNSPSC Code:
12352103

Assay

95%

mp

135 °C (lit.)

SMILES string

CS(O)(=O)=O.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(c3ccccc3)c4ccccc4

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Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H302,H311 + H331

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

484628-VAR:
484628-BULK:
484628-5G:

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Certificates of Analysis (COA)

Lot/Batch Number
20511TR
13802TR

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Margaret Walshe et al.
The Cochrane database of systematic reviews, 2(2), CD008624-CD008624 (2012-02-18)
Drooling is a common problem for children with cerebral palsy (CP). This can be distressing for these children as well as for their parents and caregivers. The consequences of drooling include risk of social rejection, damp and soiled clothing, unpleasant
Brooke E Schmeichel et al.
Neuropharmacology, 64, 321-328 (2012-07-17)
Drugs used to treat attention deficit hyperactivity disorder (ADHD) improve prefrontal cortex (PFC)-dependent cognitive function. The majority of ADHD-related treatments act either as dual norepinephrine (NE) and dopamine (DA) reuptake inhibitors (psychostimulants) or selective NE reuptake inhibitors (SNRIs). Certain benztropine
Antonio Ferragud et al.
Psychopharmacology, 207(2), 281-289 (2009-09-17)
N-substituted benztropine analogs are potent dopamine uptake inhibitors that display pharmacokinetic/dynamic properties consistent with the profile of a substitute medication for cocaine addiction. The purpose of the present experiments was to characterize in rats the addictive-like properties of one such
Gianluigi Tanda et al.
The Journal of pharmacology and experimental therapeutics, 330(3), 802-809 (2009-06-02)
Drugs that inhibit dopamine (DA) reuptake through actions at the dopamine transporter (DAT) have been proposed as candidates for development as pharmacotherapies for cocaine abuse. Accordingly, it is important to understand the potential pharmacological interactions of cocaine with other drugs
Takato Hiranita et al.
The Journal of pharmacology and experimental therapeutics, 329(2), 677-686 (2009-02-21)
Benztropine (BZT) analogs inhibit dopamine uptake but are less effective than cocaine in producing behavioral effects predicting abuse liability. The present study compared reinforcing effects of intravenous BZT analogs with those of standard monoamine uptake inhibitors and the effects of
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