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47751

Sigma-Aldrich

Fmoc-Tyr-OH

≥97.0% (HPLC)

Synonym(s):

Nα-Fmoc-L-tyrosine

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About This Item

Empirical Formula (Hill Notation):
C24H21NO5
CAS Number:
92954-90-0
Molecular Weight:
403.43
Beilstein:
3573123
MDL number:
MFCD00134890
UNSPSC Code:
12352200
PubChem Substance ID:
57651099
NACRES:
NA.26

Assay

≥97.0% (HPLC)

optical activity

[α]20/D −22±2°, c = 1% in DMF

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

OC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCC2c3ccccc3-c4ccccc24

InChI

1S/C24H21NO5/c26-16-11-9-15(10-12-16)13-22(23(27)28)25-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22,26H,13-14H2,(H,25,29)(H,27,28)/t22-/m0/s1

InChI key

SWZCTMTWRHEBIN-QFIPXVFZSA-N

related product

Product No.
Description
Pricing

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

47751-5G-F:
47751-VAR-F:
47751-BULK-F:
47751-1G-F:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Chiao-Ting Yen et al.
European journal of medicinal chemistry, 44(5), 1933-1940 (2008-12-27)
Twenty-four new dipeptide analogs (1-24) of aurantiamide acetate were designed, synthesized, and assayed for effects on superoxide anion generation and elastase release by human neutrophils in response to fMLP/CB. Among them, seven N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides (6, 9, 12, 14, 17, 18
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L-type amino acid transporter 1 (LAT1), overexpressed on the membrane of various tumor cells, is a potential target for tumor-targeting therapy. This study aimed to develop a LAT1-mediated chemotherapeutic agent. We screened doxorubicin modified by seven different large neutral amino

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