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Safety Information

399086

Sigma-Aldrich

Triethyl 2-chloro-2-phosphonoacetate

97%

Synonym(s):

Chloro(diethoxyphosphinyl)acetic acid ethyl ester

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About This Item

Linear Formula:
(C2H5O)2P(O)CH(Cl)CO2C2H5
CAS Number:
Molecular Weight:
258.64
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

form

liquid

reaction suitability

reaction type: C-C Bond Formation

refractive index

n20/D 1.446 (lit.)

bp

93-95 °C/0.01 mmHg (lit.)

density

1.21 g/mL at 25 °C (lit.)

SMILES string

CCOC(=O)C(Cl)P(=O)(OCC)OCC

InChI

1S/C8H16ClO5P/c1-4-12-8(10)7(9)15(11,13-5-2)14-6-3/h7H,4-6H2,1-3H3

InChI key

PCDXCIMROXIFBI-UHFFFAOYSA-N

Application

Reactant involved in:
  • Synthesis of purine nucleoside derivatives containing a halogen atom
  • Horner-Wadsworth-Emmons reactions
  • Scale-up production of bacterial topoisomerase inhibitors
  • Synthesis of galbonolide derivatives
  • Stereoselective Horner reaction for preparation of vinylogous peptides

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Type 3 petroleums
Hazardous rank III
Water insoluble liquid

JAN Code

399086-VAR:
399086-25ML:
399086-BULK:
399086-5ML:


Certificates of Analysis (COA)

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