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369055

Sigma-Aldrich

2-Bromo-4-fluoroaniline

97%

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About This Item

Linear Formula:
BrC6H3(F)NH2
CAS Number:
1003-98-1
Molecular Weight:
190.01
MDL number:
MFCD00042462
UNSPSC Code:
12352100
PubChem Substance ID:
24862951

Assay

97%

form

solid

refractive index

n20/D 1.583 (lit.)

bp

221 °C (lit.)

density

1.67 g/mL at 25 °C (lit.)

SMILES string

Nc1ccc(F)cc1Br

InChI

1S/C6H5BrFN/c7-5-3-4(8)1-2-6(5)9/h1-3H,9H2

InChI key

YLMFXCIATJJKQL-UHFFFAOYSA-N

General description

2-Bromo-4-fluoroaniline is an aryl fluorinated building block.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

219.2 °F - closed cup

Flash Point(C)

104 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

369055-VAR:
369055-BULK:
369055-5G:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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An efficient synthesis of enantiomerically pure aromatic-fused N-containing heterocycles from common chiral aziridines.
Chan Kim J, et al.
Tetrahedron, 66(40), 8108-8114 (2010)
Synthesis of fluorescent tetracyclic lactams by a ?one pot? three steps palladium-catalyzed borylation, Suzuki coupling (BSC) and lactamization: DNA and polynucleotides binding studies.
Queiroz M-JRP, et al.
Journal of Photochemistry and Photobiology A: Chemistry, 190(1), 45-52 (2007)
Fatma K Abdel-Wadood et al.
Archiv der Pharmazie, 347(2), 142-152 (2014-01-01)
2-Bromo-4-fluoroaniline (1) was condensed with ethyl 2-cyano-3-ethoxyacrylate (2) in ethanol to afford 3, which upon refluxing in paraffin oil at 250°C gave 8-bromo-3-cyano-6-fluoroquinoline-4(1H)-one (4). Then, compound 4 was taken as a versatile building block that allows the synthesis of thieno[3,2-c]quinoline

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