Skip to Content
Merck
All Photos(1)

Documents

Safety Information

348074

Sigma-Aldrich

2-Chloro-4-fluorobenzaldehyde

97%

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
ClC6H3(F)CHO
CAS Number:
84194-36-5
Molecular Weight:
158.56
MDL number:
MFCD00042527
UNSPSC Code:
12352100
PubChem Substance ID:
24861548
NACRES:
NA.22

Assay

97%

form

solid

bp

118-120 °C/50 mmHg (lit.)

mp

60-63 °C (lit.)

SMILES string

Fc1ccc(C=O)c(Cl)c1

InChI

1S/C7H4ClFO/c8-7-3-6(9)2-1-5(7)4-10/h1-4H

InChI key

KMQWNQKESAHDKD-UHFFFAOYSA-N

General description

2-Chloro-4-fluorobenzaldehyde is a halogen substituted benzaldehyde.

Application

2-Chloro-4-fluorobenzaldehyde may be used in the synthesis of substituted α-cyanocinnamic acid, via Knoevenagel condensation reaction. It may be used in the synthesis of 2-(2-benzimidazolyl)-3-(2-chloro-4-fluorophenyl)acrylonitrile.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

348074-5G:
348074-1G:
348074-VAR:
348074-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Biological activity and DNA binding studies of 2-substituted benzimidazo [1, 2-a] quinolines bearing different amino side chains.
Perin N, et al.
MedChemComm, 4(12), 1537-1550 (2013)
Thorsten W Jaskolla et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(34), 12200-12205 (2008-08-30)
Matrix-assisted laser desorption ionization (MALDI) has become an enabling technology for the fields of protein mass spectrometry (MS) and proteomics. Despite its widespread use, for example, in protein identification via peptide mass fingerprinting, a comprehensive model for the generation of

Articles

Knoevenagel Condensation Reaction

Knoevenagel Condensation is an organic reaction named after Emil Knoevenagel. It is a classic C-C bond formation reaction and a modification of the Aldol Condensation.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service