324108

Trimethylphosphine solution

1.0 M in THF

• Synonym(s): PMe₃, Trimethylphosphorus
• Linear Formula: (CH₃)₃P
• CAS Number: 594-09-2
• Molecular Weight: 76.08
• Beilstein: 969138
• MDL number: MFCD00008510
• UNSPSC Code: 12352128
• PubChem Substance ID: 24859423
• NACRES: NA.22

Properties

• form: liquid
• reaction suitability: reagent type: ligand; reaction type: Mitsunobu Reaction; reagent type: ligand; reaction type: Wittig Reaction
• concentration: 1.0 M in THF
• density: 0.872 g/mL at 25 °C
• functional group: phosphine
• SMILES string: CP(C)C
• InChI: 1S/C3H9P/c1-4(2)3/h1-3H3
• InChI key: YWWDBCBWQNCYNR-UHFFFAOYSA-N

Description

General description

Trimethylphosphine is the reagent used in Mitsunobu reaction. It participates in the transformation of azides into carbamates, aziridines from azidoalcohols, iminophosphoranes and aza-Wittig reaction. Electron diffraction study of trimethylphosphine has been reported.

Application

Trimethylphosphine (PMe₃) solution is the suitable reagent used in the synthesis of Fe/Te cluster type complex, Fe₆Te₈(PMe₃)₆. It may be employed as a probe to investigate the acid sites in Y-zeolite. It may be used for the synthesis of hexakis(trimethylphosphine)tris-μ-methylene-diruthenium(III).

Safety Information

• Pictograms: GHS02,GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302,H315,H319,H335,H336,H351
• Precautionary Statements: P202 - P210 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Central nervous system, Respiratory system
• Supplementary Hazards: EUH019
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): -22.0 °F - closed cup
• Flash Point(C): -30 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves