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286427

Sigma-Aldrich

L-Leucinamide hydrochloride

99%

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About This Item

Linear Formula:
(CH3)2CHCH2CH(NH2)CONH2·HCl
CAS Number:
10466-61-2
Molecular Weight:
166.65
Beilstein:
4237021
EC Number:
233-952-2
MDL number:
MFCD00013012
UNSPSC Code:
12352209
PubChem Substance ID:
24857241
NACRES:
NA.22

Assay

99%

optical activity

[α]25/D +10°, c = 5 in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

254-256 °C (lit.)

application(s)

peptide synthesis

SMILES string

Cl.CC(C)C[C@H](N)C(N)=O

InChI

1S/C6H14N2O.ClH/c1-4(2)3-5(7)6(8)9;/h4-5H,3,7H2,1-2H3,(H2,8,9);1H/t5-;/m0./s1

InChI key

VSPSRRBIXFUMOU-JEDNCBNOSA-N

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Related Categories

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

286427-1G:
286427-VAR:
286427-BULK:
286427-5G:

Certificates of Analysis (COA)

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Y L Wang et al.
Solid state nuclear magnetic resonance, 14(1), 19-32 (1999-07-17)
Proton NMR relaxation time measurements were carried out on solid tyrosine derivatives: acetyl-L-tyrosine ethyl ester (Ac-Tyroet), N-carbobenzyloxy-L-tyrosine ethyl ester (CBZ-Tyroet), N-trifluoroacetyl-L-tyrosine ethyl ester (TFAc-Tyroet) and their mixtures with L-leucinamide. It was found that spin-lattice relaxation was driven mainly by methyl
Claudio Jösch et al.
Biological chemistry, 384(2), 213-218 (2003-04-05)
Cysteinylglycine hydrolysis is a step in the metabolism of glutathione and glutathione S-conjugates. We had previously observed that in rat liver the enzymatic activity is predominantly located in the cytosol. Here we demonstrate that cytosolic leucyl aminopeptidase (EC 3.4.11.1) is
HTS, chemical hybridization, and drug design identify a chemically unique antituberculosis agent-coupling serendipity and rational approaches to drug discovery.
Jialin Mao et al.
ChemMedChem, 2(6), 811-813 (2007-04-25)
Formation of diastereomeric derivatives of 2-arylpropionic acids using L-leucinamide.
H Spahn
Journal of chromatography, 423, 334-339 (1987-12-25)
J C Hafkenscheid et al.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 23(7), 393-398 (1985-07-01)
A continuous procedure for the determination of leucine aminopeptidase is described. L-leucinamide is used as substrate and the liberated ammonia is determined with the glutamate dehydrogenase reaction. The enzyme is Mn2+-activated and 30 mumol/l MnCl2 is necessary for an optimal
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