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273880

Sigma-Aldrich

Methyl indole-4-carboxylate

99%

Synonym(s):

4-Methoxycarbonylindole

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About This Item

Empirical Formula (Hill Notation):
C10H9NO2
CAS Number:
Molecular Weight:
175.18
Beilstein:
141826
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

99%

form

solid

mp

68-71 °C (lit.)

SMILES string

COC(=O)c1cccc2[nH]ccc12

InChI

1S/C10H9NO2/c1-13-10(12)8-3-2-4-9-7(8)5-6-11-9/h2-6,11H,1H3

InChI key

WEAXQUBYRSEBJD-UHFFFAOYSA-N

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General description

The IR and UV spectra of methyl indole-4-carboxylate was studied.

Application

  • Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
  • Reactant for preparation of cytotoxic agents against multidrug-resistant cancer cells
  • Reactant for preparation of inhibitor for β-tryptase
  • Reactant for preparation of histamine H3 antagonists
  • Reactant for preparation of JNK3 MAP kinase inhibitors
  • Reactant for preparation of nucleosides

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

273880-250MG:
273880-1G:
273880-VAR:
273880-BULK:
273880-1KG:


Certificates of Analysis (COA)

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Isocarbostyrils. II. The Conversion of 2-Methyl-4-acyl-5-nitroisocarbostyrils to 2-Substituted Indole-4-carboxylic Acids.
Canadian Journal of Chemistry, 49(17), 2797-2802 (1971)

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