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154334

Sigma-Aldrich

2,5-Diaminotoluene sulfate

97%

Synonym(s):

2-Methyl-p-phenylenediamine sulfate salt, 2,5-Toluenediamine sulfate

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About This Item

Linear Formula:
CH3C6H3(NH2)2 · H2SO4
CAS Number:
Molecular Weight:
220.25
Beilstein:
3755478
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

mp

>300 °C (lit.)

SMILES string

OS(O)(=O)=O.Cc1cc(N)ccc1N

InChI

1S/C7H10N2.H2O4S/c1-5-4-6(8)2-3-7(5)9;1-5(2,3)4/h2-4H,8-9H2,1H3;(H2,1,2,3,4)

InChI key

KZTWOUOZKZQDMN-UHFFFAOYSA-N

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General description

2,5-Diaminotoluene sulfate occurs as an intermediate during hair dye formulation.

Pictograms

Skull and crossbonesEnvironment

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Skin Sens. 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

JAN Code

154334-100G:4548173107110
154334-500G:4548173107127
154334-250G:
154334-VAR:
154334-5G:4548173107134
154334-BULK:


Certificates of Analysis (COA)

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Long-term toxicity studies on oxidation hair dyes.
C Burnett et al.
Food and cosmetics toxicology, 13(3), 353-357 (1975-06-01)
H Enzmann et al.
Laryngo- rhino- otologie, 69(4), 208-212 (1990-04-01)
The middle ear is not a body site at which anaphylactic reactions (type I in the classification of Coombs and Gell) predominate. Non-IgE-mediated reactions preferentially occur in response to an allergen. Out of 64 guinea pigs, 48 were sensitized and
Andrew Scheman et al.
Dermatitis : contact, atopic, occupational, drug, 22(4), 189-192 (2011-07-26)
Finding alternative hair dyes for individuals allergic to para-phenylenediamine (PPD) has been difficult. Newer permanent and demipermanent hair dyes that have replaced PPD with para-toluenediamine sulfate (PTDS) are now available. We examined whether individuals allergic to PPD will tolerate PPD-free
David A Basketter et al.
Cutaneous and ocular toxicology, 28(3), 104-106 (2009-06-26)
p-Phenylenediamine (PPD) is an important hair dye allergen, but there remains a reasonable suspicion that other hair dye chemicals may also be responsible for a proportion of the clinical burden of hair dye allergy. To assess to what extent presently
E R Soares et al.
Environmental mutagenesis, 2(2), 111-124 (1980-01-01)
The mutagenic effects of 2,4-dinitrotoluene (2,4-DNT), purified and technical grades, 3,5-DNT, 2,4-diaminotoluene (2,4-DAT), and 2,5-DAT were tested in mice using one or more of the following: the dominant lethal assay, the sperm morphology test and/or the recessive spot test. Compounds

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