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Safety Information

147222

Sigma-Aldrich

Tetrahydrofuran

≥99.5%, contains 250 ppm BHT as inhibitor

Synonym(s):

THF, Butylene oxide, Oxolane, Tetramethylene oxide

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About This Item

Empirical Formula (Hill Notation):
C4H8O
CAS Number:
109-99-9
Molecular Weight:
72.11
Beilstein:
102391
EC Number:
203-726-8
MDL number:
MFCD00005356
UNSPSC Code:
12352005
PubChem Substance ID:
329750586

product name

Tetrahydrofuran, ≥99.5%

vapor density

2.5 (vs air)

vapor pressure

114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

Assay

≥99.5%

form

liquid

autoignition temp.

610 °F

contains

250 ppm BHT as inhibitor

expl. lim.

1.8-11.8 %

impurities

<0.030% water

refractive index

n20/D 1.407 (lit.)

bp

65-67 °C (lit.)
65-67 °C

mp

−108 °C (lit.)

solubility

water: soluble

density

0.889 g/mL at 25 °C (lit.)

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

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Legal Information

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Product No.
Description
Pricing

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Supplementary Hazards

EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

-6.2 °F - closed cup

Flash Point(C)

-21.2 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PRTR

Class I Designated Chemical Substances

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water soluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

147222-2.5L:
147222-3L:4548173105727
147222-BULK:
147222-4L:4548173248356
147222-25ML:
147222-VAR:
147222-1L:4548173248349
147222-500ML:4548173248363
147222-6X500ML:4548173248370

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Certificates of Analysis (COA)

Lot/Batch Number
11206BW
09317AW
06623CT
00802CT
00731EW

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Synthetic routes to tetrahydrofuran, tetrahydropyran, and spiroketal units of polyether antibiotics and a survey of spiroketals of other natural products.
Boivin TLB.
Tetrahedron, 43(15), 3309-3362 (1987)
Eagleson M.
Concise Encyclopedia Chemistry, 883-883 (1994)
Eagleson M.
Concise Encyclopedia Chemistry, 152-152 (1994)
Haiying Yu et al.
Biomaterials, 30(4), 508-517 (2008-11-01)
Natural bone growth greatly depends on the precedent vascular network that supplies oxygen and essential nutrients and removes metabolites. Likewise, it is crucial for tissue-engineered bone to establish a vascular network that temporally precedes new bone formation, and spatially originates
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