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128791

Sigma-Aldrich

5-Quinolinol

99%

Synonym(s):

5-Hydroxyquinoline

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About This Item

Empirical Formula (Hill Notation):
C9H7NO
CAS Number:
578-67-6
Molecular Weight:
145.16
Beilstein:
114514
EC Number:
209-428-4
MDL number:
MFCD00006792
UNSPSC Code:
12352100
PubChem Substance ID:
24847876
NACRES:
NA.22

Assay

99%

form

solid

mp

223-226 °C (lit.)

SMILES string

Oc1cccc2ncccc12

InChI

1S/C9H7NO/c11-9-5-1-4-8-7(9)3-2-6-10-8/h1-6,11H

InChI key

GYESAYHWISMZOK-UHFFFAOYSA-N

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Application

5-Quinolinol (5-Hydroxyquinoline) was used as an internal standard in the reaction to measure morphine concentration in serum or plasma. It was also used as a lipophilic chelator and it decreased the rate of deoxygenation.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

128791-VAR:
128791-250MG:
128791-BULK:
128791-1G:

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Certificates of Analysis (COA)

Lot/Batch Number
16525MH
12003PW
01426MX
08927ED
13626JN

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8-Hydroxyquinoline

Sigma-Aldrich

H6878

8-Hydroxyquinoline

M Hollstein et al.
Journal of the National Cancer Institute, 60(2), 405-410 (1978-02-01)
Quinoline, a hepatocarcinogen in rats, and 23 quinoline derivatives were tested for mutagenic activity with the Ames Salmonella typhimurium assay. Quinoline, 5-hydroxyquinoline, and 8-hydroxyquinoline were mutagenic in strain TA 100 when Aroclor 1254-induced rat (male outbred Sprague-Dawley) liver homogenate was
H Vandenberghe et al.
Therapeutic drug monitoring, 4(3), 307-314 (1982-01-01)
In this report we describe a rapid and sensitive micromethod using high performance liquid chromatography (HPLC) with electrochemical detection (ED) to measure morphine concentration in serum or plasma. The separation of morphine and the internal standard 5-hydroxyquinoline, from interfering compounds
R Deslauriers et al.
Biochimica et biophysica acta, 886(3), 319-326 (1986-05-29)
A spectrophotometric assay has been devised to measure oxygen consumption non-invasively in intact murine red cells parasitized by Plasmodium berghei. The method uses oxyhemoglobin in the erythrocytes both as a source of oxygen and as an indicator of oxygen consumption.
Markus Brinkmann et al.
Chemical research in toxicology, 32(4), 698-707 (2019-03-22)
Hydroxylation of polyaromatic compounds through cytochromes P450 (CYPs) is known to result in potentially estrogenic transformation products. Recently, there has been an increasing awareness of the importance of alternative pathways such as aldehyde oxidases (AOX) or N-methyltransferases (NMT) in bioactivation
Nihal Kuş et al.
The journal of physical chemistry. A, 119(24), 6296-6308 (2015-05-31)
The structure, infrared spectrum, and photochemistry of 5-hydroxyquinoline (5HQ) were studied by matrix isolation infrared spectroscopy, complemented by theoretical calculations performed at the DFT(B3LYP)/6-311++G(d,p) level of approximation. According to the calculations, the trans conformer of 5HQ (with the OH group
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