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Merck

HTR5A

5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled

Synonyms:
5-HT5A
Species:
Human HTR5A (3361), Mouse Htr5a (15563), Rat Htr5a (25689), cow HTR5A (541200), Horse HTR5A (100063709), domestic cat HTR5A (101084611), Zebrafish htr5a (100038775), dog HTR5A (482814), sheep HTR5A (101116905), naked mole-rat Htr5a (101723065) ...More
UniProtKB ID:
P47898, Q2M2D2
Gene ID:
  • Human(3361) Summary: The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008]
  • Mouse(15563) 5-hydroxytryptamine (serotonin) receptor 5A
  • Rat(25689) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • cow(541200) 5-hydroxytryptamine (serotonin) receptor 5A
  • Horse(100063709) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • domestic cat(101084611) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • Zebrafish(100038775) 5-hydroxytryptamine (serotonin) receptor 5A
  • dog(482814) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • sheep(101116905) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • naked mole-rat(101723065) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • domestic guinea pig(100379278) 5-hydroxytryptamine (serotonin) receptor 5A
  • chicken(428409) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled

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Small Molecule - Agonist

Product Number
Description
Species
C117
5-Carboxamidotryptamine maleate salt, powder, ≥98% (HPLC),
Species
human, rat
F112
(+)-Fenfluramine hydrochloride, ,
Species
human
Q1004
Quipazine maleate salt, ,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
D9190
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
C117
5-Carboxamidotryptamine maleate salt, powder, ≥98% (HPLC),
Species
human, rat
A0590000
Amisulpride, European Pharmacopoeia (EP) Reference Standard,
Species
human
A2729
Amisulpride, ≥98% (HPLC),
Species
human
BP1090
Amisulpride, British Pharmacopoeia (BP) Reference Standard,
Species
human
Y0001534
Amisulpride for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB2900036
Anti-HTR5A (AB1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
SAB2900037
Anti-HTR5A (AB2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, dog, guinea pig, horse, human, monkey, mouse, rat
Application
ELISA
immunohistochemistry
SAB4501483
Anti-HTR5A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
SAB2900156
Anti-HTR5A antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

Small Molecule - Blocker

Product Number
Description
Species
T3146
Trimipramine maleate salt, ≥98% (TLC), powder,
Species
human
Z101
Zimelidine dihydrochloride, solid,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Species
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Species
human
F2802
Fluvoxamine maleate, solid,
Species
human
S6319
Sertraline hydrochloride, ≥98% (HPLC),
Species
human
C7861
Citalopram hydrobromide, ≥98% (HPLC),
Species
human

Small Molecule - Ligand

Product Number
Description
Species
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

Product Number
Description
Species
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Precursor

Product Number
Description
Species
H9772
5-Hydroxy-L-tryptophan, powder,
Species
human

Proteins

Product Number
Description
Species
HTS141M
ChemiSCREEN Membrane Preparation Recombinant Human 5-HT5A Serotonin Receptor, ,
Species
human

esiRNA

Product Number
Description
Species
EHU104651
MISSION® esiRNA, targeting human HTR5A,
Species
human