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T2684

Sigma-Aldrich

TiterMax® Gold Adjuvant

liquid

Synonym(s):

TiterMax adjuvant

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.46

conjugate

unconjugated

Quality Level

form

liquid

availability

not available in Japan

storage temp.

2-8°C

General description

TiterMax Gold Adjuvant contains three essential ingredients: a new block copolymer, CRL-8300, squalene (a metabolizable oil) and a sorbitan monooleate.

Application

TiterMax® Gold Adjuvant has been used:
  • to emulsify soluble antigen-1 (Ag-1) to immunize animals to generate fully human monoclonal antibodies from XenoMouse strains
  • to inject GST-dGIPC (Drosophila homolog of GAIP interacting protein) protein into rats for generating antibodies against dGIPC protein
  • with Drosophila CtBP (dCtBP) protein in phosphate-buffered saline (PBS) to subcutaneously inject in a New Zealand female rabbit

Biochem/physiol Actions

Specific proteins can be emulsified with equal volume of TiterMax® Gold Adjuvant to immunize lab animals and extract antibodies from them.
TiterMax Gold is a new and improved water-in-oil adjuvant. By developing a new block copolymer and eliminating the silica from the formulation, TiterMax Gold appears to be less toxic and more effective than TiterMax Classic. The optimum volume of TiterMax Gold for an emulsion is twice that of TiterMax Classic.

Legal Information

TiterMax is a registered trademark of TiterMax USA, Inc

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Description
Pricing

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jihyun Kim et al.
Biochemical and biophysical research communications, 402(3), 565-570 (2010-10-30)
To identify genes that function in the adult neural system, we screened pools of P element-mediated mutants and tested locomotor activity of homozygous flies. Of 1014 P element-mutagenized lines, 638 were homozygous viable. These lines were tested for climbing ability
Seppo Parkkila et al.
BMC clinical pathology, 8, 2-2 (2008-02-20)
S100P is a Ca2+ binding protein overexpressed in a variety of cancers, and thus, has been considered a potential tumor biomarker. Very little has been studied about its normal expression and functions. We examined S100P expression in normal human tissues
Elwira Pyz et al.
European journal of immunology, 38(4), 1157-1163 (2008-03-20)
Inhibitory receptors are required for the control of cellular activation and they play essential roles in regulating homeostasis and immunity. We previously identified a human inhibitory C-type lectin-like receptor, MICL (CLEC12A), a heavily glycosylated monomer predominantly expressed on myeloid cells.
Fernando Garces et al.
Cell reports, 30(6), 1714-1723 (2020-02-13)
Calcitonin-gene-related peptide (CGRP) plays a key role in migraine pathophysiology. Aimovig (erenumab; erenumab-aooe in the United States) is the only US Food and Drug Administration (FDA)-approved monoclonal antibody (mAb) therapy against the CGRP receptor (CGRPR) for the prevention of migraine.
Andrew W Drake et al.
Analytical biochemistry, 328(1), 35-43 (2004-04-15)
Two biophysical methods, Biacore and KinExA, were used to kinetically and thermodynamically characterize high-affinity antigen/antibody complexes. Three to five independent experiments were performed on each platform with three different antigen/antibody complexes possessing nanomolar to picomolar equilibrium dissociation constants. By monitoring

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